PDF(Pubmed)
Abstract：
UNASSIGNED: Researchers using herbs and natural products to find new drugs often prefer flavonoids because of their potential as antioxidants and anti-inflammatories. The planned review addressed baicalein research findings in detail. This manuscript provides a complete review of baicalein\'s potential pharmacological effects along with several molecular targets for better understanding of its therapeutic activities.
UNASSIGNED: We targeted the review on in vitro and in vivo studies reported on baicalein. For this, the literature is gathered from the database available on search engines like PubMed, ScienceDirect, Scopus, and Google Scholar up to 21 December 2023. The keywords \"Scutellaria baicalensis\", \"Oroxylum indicum\", \"Neuroprotective\", \"Cardioprotective\", \"Toxicity studies\", and \"Baicalein\" were used to fetch the content.
UNASSIGNED: Baicalein\'s molecular receptor binding approach has shown anticancer, antidiabetic, antimicrobial, antiaging, neuroprotective, cardioprotective, respiratory protective, gastroprotective, hepatic protective, and renal protective effects. The synergistic effects of this drug with other selective herbs are also contributed towards significant therapeutic potential.
UNASSIGNED: This systematic review article from a contemporary and scientific perspective offers fresh insight into S. baicalensis, O. indicum, and its bioactive component baicalein as a potential complementary medicine. Baicalein may be transformed into more efficacious and acceptable evidence-based medicine. However, we recommend more clinical and mechanistic approaches to confirm safety and efficacy of baicalein.
UNASSIGNED: We targeted the review on in vitro and in vivo studies reported on baicalein. For this, the literature is gathered from the database available on search engines like PubMed, ScienceDirect, Scopus, and Google Scholar up to 21 December 2023. The keywords \"Scutellaria baicalensis\", \"Oroxylum indicum\", \"Neuroprotective\", \"Cardioprotective\", \"Toxicity studies\", and \"Baicalein\" were used to fetch the content.
UNASSIGNED: Baicalein\'s molecular receptor binding approach has shown anticancer, antidiabetic, antimicrobial, antiaging, neuroprotective, cardioprotective, respiratory protective, gastroprotective, hepatic protective, and renal protective effects. The synergistic effects of this drug with other selective herbs are also contributed towards significant therapeutic potential.
UNASSIGNED: This systematic review article from a contemporary and scientific perspective offers fresh insight into S. baicalensis, O. indicum, and its bioactive component baicalein as a potential complementary medicine. Baicalein may be transformed into more efficacious and acceptable evidence-based medicine. However, we recommend more clinical and mechanistic approaches to confirm safety and efficacy of baicalein.
摘要：
■使用草药和天然产品寻找新药的研究人员通常更喜欢类黄酮，因为它们具有作为抗氧化剂和抗炎药的潜力。计划中的审查详细讨论了黄芩素的研究结果。本手稿提供了黄芩素的潜在药理作用以及几个分子靶标的完整综述，以更好地了解其治疗活性。
■我们针对黄芩素的体外和体内研究进行了综述。为此，文献是从PubMed等搜索引擎上的数据库中收集的，ScienceDirect,Scopus,和谷歌学者截至2023年12月21日。关键词\"黄芩\",\"象牙树\",“神经保护”，“心脏保护”，“毒性研究”，和“Baicalein”用于获取内容。
■黄芩素的分子受体结合方法已显示出抗癌作用，抗糖尿病药,抗菌，抗衰老,神经保护,心脏保护,呼吸保护,胃保护,肝保护,和肾脏保护作用。该药物与其他选择性草药的协同作用也有助于显著的治疗潜力。
■这篇系统的综述文章从当代和科学的角度为黄芩提供了新的见解，O.indicum,及其生物活性成分黄芩素作为一种潜在的补充药物。黄芩素可以转化为更有效和可接受的循证药物。然而,我们推荐更多的临床和机械方法来确认黄芩素的安全性和有效性.
■我们针对黄芩素的体外和体内研究进行了综述。为此，文献是从PubMed等搜索引擎上的数据库中收集的，ScienceDirect,Scopus,和谷歌学者截至2023年12月21日。关键词\"黄芩\",\"象牙树\",“神经保护”，“心脏保护”，“毒性研究”，和“Baicalein”用于获取内容。
■黄芩素的分子受体结合方法已显示出抗癌作用，抗糖尿病药,抗菌，抗衰老,神经保护,心脏保护,呼吸保护,胃保护,肝保护,和肾脏保护作用。该药物与其他选择性草药的协同作用也有助于显著的治疗潜力。
■这篇系统的综述文章从当代和科学的角度为黄芩提供了新的见解，O.indicum,及其生物活性成分黄芩素作为一种潜在的补充药物。黄芩素可以转化为更有效和可接受的循证药物。然而,我们推荐更多的临床和机械方法来确认黄芩素的安全性和有效性.
