关键词: Hanseniaspora MALDI-TOF MS Streptococcus agalactiae apiculate yeasts opportunistic pathogens

Mesh : Humans Female Pregnancy Brazil Adult Pregnancy Complications, Infectious / microbiology diagnosis Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Vagina / microbiology DNA, Ribosomal / genetics Sequence Analysis, DNA Streptococcus agalactiae / isolation & purification genetics classification Diabetes, Gestational / microbiology diagnosis Young Adult

来  源:   DOI:10.3389/fcimb.2024.1394663   PDF(Pubmed)

Abstract:
In this study, we report the first isolation of Hanseniaspora opuntiae obtained from four pregnant women in Brazil. Clinical isolates were obtained from four samples taken between 35 and 37 gestational weeks, as part of the routine antenatal care for maternal colonization screening for Streptococcus agalactiae group B. The patients were immunocompetent, with two of them diagnosed with gestational diabetes mellitus. Species identification was performed by MALDI-TOF MS and rDNA sequencing. While Hanseniaspora species have not traditionally been considered a typical opportunist pathogen, our findings emphasize the importance of investigating and screening for Hanseniaspora in pregnant populations, highlighting H. opuntiae as a potential agent of human infections.
摘要:
在这项研究中,我们报告了从巴西的四名孕妇中获得的Hanseniassporaopuntiae的首次分离。从35至37孕周之间采集的四个样本中获得临床分离株,作为常规产前护理的一部分,用于孕妇建群筛查无乳链球菌B组。其中两人被诊断为妊娠期糖尿病。通过MALDI-TOFMS和rDNA测序进行物种鉴定。虽然Hanseniaspora物种传统上不被认为是典型的机会主义病原体,我们的发现强调了在怀孕人群中调查和筛查Hanseniaspora的重要性,强调H.opuntiae是人类感染的潜在病原体。
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