PDF(Pubmed)
Abstract：
UNASSIGNED: Drawing on the principles of wrist-ankle acupuncture (WAA), our research team has developed a portable device for WAA point compression, termed the acupressure wrist-ankle strap (AWA). The current study aims to evaluate the efficacy of the AWA in alleviating pain associated with primary dysmenorrhea.
UNASSIGNED: A single-blind, randomized clinical trial was conducted from April 1, 2019, to December 31, 2019. 78 participants with primary dysmenorrhea were recruited from Shanghai University of Traditional Chinese Medicine. All participants were treated on the first day of menstruation for 30 min. Participants in the AWA group used the AWA, the internal side of which is equipped with a tip compression component, while participants in the non-acupressure wrist-ankle acupuncture(NAWA)group used the NAWA, with the inside tip pressing parts removed. The main outcome was the difference in visual analogue scale (VAS) score between baseline and 30 minutes after randomization.
UNASSIGNED: A total of 78 participants aged 18 to 30 years were included in the intention-to-treat analyses. The VAS scores (mean [standard deviation]) in the AWA group were significantly lower than those in the NAWA group at each time point of intervention (5 minutes: 95% CI, [-1.27 to -0.68], p < 0.001; 10 minutes: 95% CI, [-2.34 to -1.51], p < 0.001; 30 minutes: 95% CI, [-3.74 to -2.72], p < 0.001). In the AWA group, 16 participants reported \"obvious relief\" of dysmenorrhea pain while 23 did not; the average onset time of analgesia they reported were (21.50 ± 3.65) min, while no subjects in NAWA group reported obvious pain relief. The pain threshold (mean [standard deviation]) at SP9 of both sides in AWA group decreased significantly after intervention that in NAWA group (Left: 95% CI, [-5.02 to -1.81], p < 0.001; Right: 95% CI, [-7.67 to -4.24], p < 0.001). There was no significant change in the temperature at CV4 in either group (95% CI, [-0.63 to -0.66], p = 0.970).
UNASSIGNED: This trial substantiates our hypothesis that the AWA provides immediate analgesic effects. The AWA represents an effective and safe non-invasive physical therapy option, which patients can self-administer to alleviate abdominal pain.
UNASSIGNED: A single-blind, randomized clinical trial was conducted from April 1, 2019, to December 31, 2019. 78 participants with primary dysmenorrhea were recruited from Shanghai University of Traditional Chinese Medicine. All participants were treated on the first day of menstruation for 30 min. Participants in the AWA group used the AWA, the internal side of which is equipped with a tip compression component, while participants in the non-acupressure wrist-ankle acupuncture(NAWA)group used the NAWA, with the inside tip pressing parts removed. The main outcome was the difference in visual analogue scale (VAS) score between baseline and 30 minutes after randomization.
UNASSIGNED: A total of 78 participants aged 18 to 30 years were included in the intention-to-treat analyses. The VAS scores (mean [standard deviation]) in the AWA group were significantly lower than those in the NAWA group at each time point of intervention (5 minutes: 95% CI, [-1.27 to -0.68], p < 0.001; 10 minutes: 95% CI, [-2.34 to -1.51], p < 0.001; 30 minutes: 95% CI, [-3.74 to -2.72], p < 0.001). In the AWA group, 16 participants reported \"obvious relief\" of dysmenorrhea pain while 23 did not; the average onset time of analgesia they reported were (21.50 ± 3.65) min, while no subjects in NAWA group reported obvious pain relief. The pain threshold (mean [standard deviation]) at SP9 of both sides in AWA group decreased significantly after intervention that in NAWA group (Left: 95% CI, [-5.02 to -1.81], p < 0.001; Right: 95% CI, [-7.67 to -4.24], p < 0.001). There was no significant change in the temperature at CV4 in either group (95% CI, [-0.63 to -0.66], p = 0.970).
UNASSIGNED: This trial substantiates our hypothesis that the AWA provides immediate analgesic effects. The AWA represents an effective and safe non-invasive physical therapy option, which patients can self-administer to alleviate abdominal pain.
摘要：
■根据腕踝针（WAA）的原理，我们的研究小组开发了一种便携式设备，用于WAA点压缩，称为指压腕踝带（AWA）。本研究旨在评估AWA缓解原发性痛经相关疼痛的疗效。
■单盲，随机临床试验于2019年4月1日至2019年12月31日进行.从上海中医药大学招募78例原发性痛经患者。所有参与者在月经的第一天治疗30分钟。AWA小组的参与者使用AWA，其内侧装有尖端压缩组件，而非指压腕踝针（NAWA）组的参与者使用NAWA，内部尖端按压部件被移除。主要结果是基线和随机分组后30分钟之间的视觉模拟量表（VAS）评分差异。
■共有78名18至30岁的参与者被纳入意向治疗分析。在干预的每个时间点，AWA组的VAS评分（平均值[标准差]）均显着低于NAWA组（5分钟：95％CI，[-1.27to-0.68]，p<0.001；10分钟：95%CI，[-2.34至-1.51]，p<0.001；30分钟：95%CI，[-3.74至-2.72]，p<0.001)。在AWA组中,16例参与者报告痛经疼痛“明显缓解”，23例没有；他们报告的镇痛平均起效时间为（21.50±3.65）分钟，而NAWA组没有受试者报告疼痛明显缓解。AWA组在干预后两侧的SP9疼痛阈值（平均值[标准差]）显着下降，而NAWA组（左：95％CI，[-5.02至-1.81]，p<0.001；右：95%CI，[-7.67至-4.24]，p<0.001)。两组中CV4时的温度均无明显变化（95％CI，[-0.63至-0.66]，p=0.970)。
■该试验证实了我们的假设，即AWA可立即提供镇痛作用。AWA代表了一种有效且安全的非侵入性物理治疗选择，患者可以自行用药以缓解腹痛。
■单盲，随机临床试验于2019年4月1日至2019年12月31日进行.从上海中医药大学招募78例原发性痛经患者。所有参与者在月经的第一天治疗30分钟。AWA小组的参与者使用AWA，其内侧装有尖端压缩组件，而非指压腕踝针（NAWA）组的参与者使用NAWA，内部尖端按压部件被移除。主要结果是基线和随机分组后30分钟之间的视觉模拟量表（VAS）评分差异。
■共有78名18至30岁的参与者被纳入意向治疗分析。在干预的每个时间点，AWA组的VAS评分（平均值[标准差]）均显着低于NAWA组（5分钟：95％CI，[-1.27to-0.68]，p<0.001；10分钟：95%CI，[-2.34至-1.51]，p<0.001；30分钟：95%CI，[-3.74至-2.72]，p<0.001)。在AWA组中,16例参与者报告痛经疼痛“明显缓解”，23例没有；他们报告的镇痛平均起效时间为（21.50±3.65）分钟，而NAWA组没有受试者报告疼痛明显缓解。AWA组在干预后两侧的SP9疼痛阈值（平均值[标准差]）显着下降，而NAWA组（左：95％CI，[-5.02至-1.81]，p<0.001；右：95%CI，[-7.67至-4.24]，p<0.001)。两组中CV4时的温度均无明显变化（95％CI，[-0.63至-0.66]，p=0.970)。
■该试验证实了我们的假设，即AWA可立即提供镇痛作用。AWA代表了一种有效且安全的非侵入性物理治疗选择，患者可以自行用药以缓解腹痛。
