PDF(Pubmed)
Abstract：
OBJECTIVE: The aim of this study is to elucidate the factors contributing to the occurrence of retinal detachment (RD) following prophylactic vitrectomy in cases of acute retinal necrosis (ARN) syndrome.
METHODS: A retrospective examination was undertaken, encompassing the medical records of patients diagnosed with ARN who underwent prophylactic vitreous intervention at the Ophthalmology Department of Wuhan University Renmin Hospital East Campus between October 2019 and September 2023. Subsequently, patients who manifested RD in the postoperative period were identified, and a comprehensive analysis was conducted to ascertain the factors underlying the occurrence of RD post-surgery.
RESULTS: This study comprised 14 cases (involving 14 eyes) of patients diagnosed with ARN who underwent prophylactic vitreous intervention. The findings revealed that 4 patients experienced postoperative RD, resulting in an incidence rate of 28.57%. Notably, among these cases, 3 cases of RD manifested in the presence of silicone oil, while 1 case occurred subsequent to the removal of silicone oil. All 4 cases of RD exhibited varied degrees of proliferative vitreoretinopathy. Following the occurrence of RD, all patients underwent a secondary vitreous intervention coupled with silicone oil tamponade, leading to successful reattachment of the retina. However, despite these interventions, there was no significant enhancement observed in postoperative visual outcomes when compared to preoperative levels.
CONCLUSIONS: RD following prophylactic vitrectomy in cases of ARN is not an infrequent occurrence and is primarily linked to the postoperative onset of proliferative vitreoretinopathy.
METHODS: A retrospective examination was undertaken, encompassing the medical records of patients diagnosed with ARN who underwent prophylactic vitreous intervention at the Ophthalmology Department of Wuhan University Renmin Hospital East Campus between October 2019 and September 2023. Subsequently, patients who manifested RD in the postoperative period were identified, and a comprehensive analysis was conducted to ascertain the factors underlying the occurrence of RD post-surgery.
RESULTS: This study comprised 14 cases (involving 14 eyes) of patients diagnosed with ARN who underwent prophylactic vitreous intervention. The findings revealed that 4 patients experienced postoperative RD, resulting in an incidence rate of 28.57%. Notably, among these cases, 3 cases of RD manifested in the presence of silicone oil, while 1 case occurred subsequent to the removal of silicone oil. All 4 cases of RD exhibited varied degrees of proliferative vitreoretinopathy. Following the occurrence of RD, all patients underwent a secondary vitreous intervention coupled with silicone oil tamponade, leading to successful reattachment of the retina. However, despite these interventions, there was no significant enhancement observed in postoperative visual outcomes when compared to preoperative levels.
CONCLUSIONS: RD following prophylactic vitrectomy in cases of ARN is not an infrequent occurrence and is primarily linked to the postoperative onset of proliferative vitreoretinopathy.
摘要：
目的：本研究的目的是阐明急性视网膜坏死（ARN）综合征患者预防性玻璃体切除术后视网膜脱离（RD）发生的因素。
方法：进行回顾性检查，包括2019年10月至2023年9月在武汉大学人民医院东校区眼科接受预防性玻璃体干预的ARN患者的医疗记录.随后，确定在术后期间出现RD的患者，并进行了综合分析，以确定术后RD发生的潜在因素。
结果：本研究包括14例（涉及14只眼）接受预防性玻璃体干预的ARN患者。结果显示，4例患者发生术后RD，发病率为28.57%。值得注意的是,在这些案件中，3例RD表现为硅油的存在，而1例发生在硅油取出后。4例RD均表现为不同程度的增生性玻璃体视网膜病变。RD发生后，所有患者都接受了二次玻璃体介入以及硅油填塞，导致视网膜成功的重新附着。然而,尽管有这些干预措施，与术前水平相比,术后视力结果没有显著增强.
结论：ARN患者行预防性玻璃体切除术后的RD并非罕见，主要与术后发生增生性玻璃体视网膜病变有关。
方法：进行回顾性检查，包括2019年10月至2023年9月在武汉大学人民医院东校区眼科接受预防性玻璃体干预的ARN患者的医疗记录.随后，确定在术后期间出现RD的患者，并进行了综合分析，以确定术后RD发生的潜在因素。
结果：本研究包括14例（涉及14只眼）接受预防性玻璃体干预的ARN患者。结果显示，4例患者发生术后RD，发病率为28.57%。值得注意的是,在这些案件中，3例RD表现为硅油的存在，而1例发生在硅油取出后。4例RD均表现为不同程度的增生性玻璃体视网膜病变。RD发生后，所有患者都接受了二次玻璃体介入以及硅油填塞，导致视网膜成功的重新附着。然而,尽管有这些干预措施，与术前水平相比,术后视力结果没有显著增强.
结论：ARN患者行预防性玻璃体切除术后的RD并非罕见，主要与术后发生增生性玻璃体视网膜病变有关。
