关键词: Adipocytes Adipose tissue plasticity Breast cancers Cancers de la prostate Cancers du sein Fibrose Fibrosis Inflammation Mammary adipose tissue Obesity Obésité Periprostatic adipose tissue Plasticité du tissu adipeux Prostate cancers Tissu adipeux mammaire Tissu adipeux péri-prostatique

Mesh : Humans Adipose Tissue / physiology Female Obesity / physiopathology Neoplasms / pathology Animals Breast / physiology pathology Breast Neoplasms / pathology Mammary Glands, Human / physiology pathology Intra-Abdominal Fat Subcutaneous Fat / physiology pathology

来  源:   DOI:10.1016/j.ando.2024.05.016

Abstract:
In addition to the major subcutaneous and visceral adipose tissues (AT), other adipose depots are dispersed throughout the body and are found in close interaction with proximal organs such as mammary and periprostatic AT (MAT and PPAT respectively). These ATs have an effect on proximal organ function during physiological processes and diseases such as cancer. We highlighted here some of their most distinctive features in terms of tissular organization and responses to external stimuli and discussed how obesity affects them based on our current knowledge.
摘要:
除了主要的皮下和内脏脂肪组织(AT),其他脂肪库分散在整个身体,并发现与近端器官如乳腺和前列腺周围的AT(分别为MAT和PPAT)密切相互作用。这些ATs在生理过程和诸如癌症的疾病期间对近端器官功能有影响。我们在这里强调了它们在组织组织和对外部刺激的反应方面的一些最鲜明的特征,并根据我们目前的知识讨论了肥胖如何影响它们。
公众号