Abstract：
BACKGROUND: TSH and ACTH are crucial hormones for diagnosing thyroid and adrenal diseases, and incorrect test reports can cause significant harm to patients.
METHODS: The TSH and ACTH levels on the testing system of our laboratory were measured using \"sandwich\" assays. The patient had heterophilic antibodies in their body, causing a false increase in TSH and ACTH levels.
RESULTS: TSH on the Abbott platform was 59.7 μIU/mL and on the Roche platform it was 4.33 μIU/mL. After pretreatment with HBR it was 3.95 μIU/mL; ACTH on the SIEMENS platform was 263.5 pg/mL, on the Abbott platform it was 47.6 pg/mL. After pretreatment with HBR it was 36.5 pg/mL.
CONCLUSIONS: The patient\'s serum contains heterophilic antibodies, which interfere with the TSH and ACTH tested by this method.
METHODS: The TSH and ACTH levels on the testing system of our laboratory were measured using \"sandwich\" assays. The patient had heterophilic antibodies in their body, causing a false increase in TSH and ACTH levels.
RESULTS: TSH on the Abbott platform was 59.7 μIU/mL and on the Roche platform it was 4.33 μIU/mL. After pretreatment with HBR it was 3.95 μIU/mL; ACTH on the SIEMENS platform was 263.5 pg/mL, on the Abbott platform it was 47.6 pg/mL. After pretreatment with HBR it was 36.5 pg/mL.
CONCLUSIONS: The patient\'s serum contains heterophilic antibodies, which interfere with the TSH and ACTH tested by this method.
摘要：
背景：TSH和ACTH是诊断甲状腺和肾上腺疾病的关键激素，不正确的检测报告会对患者造成重大伤害。
方法：我们实验室的测试系统上的TSH和ACTH水平是使用“三明治”测定法测量的。病人体内有异嗜性抗体,导致TSH和ACTH水平的虚假增加。
结果：在雅培平台上的TSH为59.7μIU/mL，在罗氏平台上的TSH为4.33μIU/mL。用HBR预处理后为3.95μIU/mL；在SIEMENS平台上的ACTH为263.5pg/mL，在雅培平台上,其为47.6pg/mL。用HBR预处理后为36.5pg/mL。
结论：患者血清中含有异源性抗体，干扰通过该方法测试的TSH和ACTH。
方法：我们实验室的测试系统上的TSH和ACTH水平是使用“三明治”测定法测量的。病人体内有异嗜性抗体,导致TSH和ACTH水平的虚假增加。
结果：在雅培平台上的TSH为59.7μIU/mL，在罗氏平台上的TSH为4.33μIU/mL。用HBR预处理后为3.95μIU/mL；在SIEMENS平台上的ACTH为263.5pg/mL，在雅培平台上,其为47.6pg/mL。用HBR预处理后为36.5pg/mL。
结论：患者血清中含有异源性抗体，干扰通过该方法测试的TSH和ACTH。
