PDF(Pubmed)
Abstract：
UNASSIGNED: Clinicians face difficulties in making treatment decisions for unspecified anxiety disorder due to the absence of any treatment guidelines. The objective of this study was to investigate how familiar and how often primary care physicians use pharmacological and nonpharmacological approaches to manage the disorder.
UNASSIGNED: A survey was conducted among 117 primary care physicians in Japan who were asked to assess the familiarity of using each treatment option for unspecified anxiety disorder on a binary response scale (0 = \"unfamiliar,\" 1 = \"familiar\") and the frequency on a nine-point Likert scale (1 = \"never used,\" 9 = \"frequently used\").
UNASSIGNED: While several benzodiazepine anxiolytics were familiar to primary care physicians, the frequencies of prescribing them, including alprazolam (4.6 ± 2.6), ethyl loflazepate (3.6 ± 2.4), and clotiazepam (3.5 ± 2.3), were low. In contrast, certain nonpharmacological options, including lifestyle changes (5.4 ± 2.3), coping strategies (5.1 ± 2.7), and psychoeducation for anxiety (5.1 ± 2.7), were more commonly utilized, but to a modest extent. When a benzodiazepine anxiolytic drug failed to be effective, primary care physicians selected the following management strategies to a relatively high degree: differential diagnosis (6.4 ± 2.4), referral to a specialist hospital (5.9 ± 2.5), lifestyle changes (5.2 ± 2.5), and switching to selective serotonin reuptake inhibitor (5.1 ± 2.4).
UNASSIGNED: Primary care physicians exercise caution when prescribing benzodiazepine anxiolytics for unspecified anxiety disorder. Nonpharmacological interventions and switching to SSRI are modestly employed as primary treatment options and alternatives to benzodiazepine anxiolytics. To ensure the safe and effective treatment of unspecified anxiety disorder in primary care, more information should be provided from field experts.
UNASSIGNED: A survey was conducted among 117 primary care physicians in Japan who were asked to assess the familiarity of using each treatment option for unspecified anxiety disorder on a binary response scale (0 = \"unfamiliar,\" 1 = \"familiar\") and the frequency on a nine-point Likert scale (1 = \"never used,\" 9 = \"frequently used\").
UNASSIGNED: While several benzodiazepine anxiolytics were familiar to primary care physicians, the frequencies of prescribing them, including alprazolam (4.6 ± 2.6), ethyl loflazepate (3.6 ± 2.4), and clotiazepam (3.5 ± 2.3), were low. In contrast, certain nonpharmacological options, including lifestyle changes (5.4 ± 2.3), coping strategies (5.1 ± 2.7), and psychoeducation for anxiety (5.1 ± 2.7), were more commonly utilized, but to a modest extent. When a benzodiazepine anxiolytic drug failed to be effective, primary care physicians selected the following management strategies to a relatively high degree: differential diagnosis (6.4 ± 2.4), referral to a specialist hospital (5.9 ± 2.5), lifestyle changes (5.2 ± 2.5), and switching to selective serotonin reuptake inhibitor (5.1 ± 2.4).
UNASSIGNED: Primary care physicians exercise caution when prescribing benzodiazepine anxiolytics for unspecified anxiety disorder. Nonpharmacological interventions and switching to SSRI are modestly employed as primary treatment options and alternatives to benzodiazepine anxiolytics. To ensure the safe and effective treatment of unspecified anxiety disorder in primary care, more information should be provided from field experts.
摘要：
由于缺乏任何治疗指南，临床医生在为未指明的焦虑症做出治疗决定时面临困难。这项研究的目的是调查初级保健医生使用药理学和非药理学方法来治疗疾病的熟悉程度和频率。
■在日本的117名初级保健医生中进行了一项调查，他们被要求以二元反应量表（0=“不熟悉，\"1=\"熟悉\")和九点李克特量表上的频率(1=\"从未使用过，\"9=\"常用\")。
虽然初级保健医生熟悉几种苯二氮卓抗焦虑药，开处方的频率，包括阿普唑仑（4.6±2.6），氯氟嗪乙酯(3.6±2.4),和氯噻嗪（3.5±2.3），很低。相比之下,某些非药理学选择，包括生活方式的改变（5.4±2.3），应对策略(5.1±2.7)，和焦虑的心理教育（5.1±2.7），更常用，但在一定程度上。当苯二氮卓抗焦虑药物无效时，初级保健医生选择了以下相对较高的管理策略：鉴别诊断（6.4±2.4），转诊至专科医院（5.9±2.5），生活方式改变（5.2±2.5），并转换为选择性5-羟色胺再摄取抑制剂（5.1±2.4）。
■初级保健医生在处方苯二氮卓抗焦虑药以治疗未指明的焦虑症时要谨慎。非药物干预和改用SSRI被适度地用作苯二氮卓抗焦虑药的主要治疗选择和替代品。为了确保在初级保健中安全有效地治疗未指明的焦虑症，更多的信息应该从领域专家那里提供。
■在日本的117名初级保健医生中进行了一项调查，他们被要求以二元反应量表（0=“不熟悉，\"1=\"熟悉\")和九点李克特量表上的频率(1=\"从未使用过，\"9=\"常用\")。
虽然初级保健医生熟悉几种苯二氮卓抗焦虑药，开处方的频率，包括阿普唑仑（4.6±2.6），氯氟嗪乙酯(3.6±2.4),和氯噻嗪（3.5±2.3），很低。相比之下,某些非药理学选择，包括生活方式的改变（5.4±2.3），应对策略(5.1±2.7)，和焦虑的心理教育（5.1±2.7），更常用，但在一定程度上。当苯二氮卓抗焦虑药物无效时，初级保健医生选择了以下相对较高的管理策略：鉴别诊断（6.4±2.4），转诊至专科医院（5.9±2.5），生活方式改变（5.2±2.5），并转换为选择性5-羟色胺再摄取抑制剂（5.1±2.4）。
■初级保健医生在处方苯二氮卓抗焦虑药以治疗未指明的焦虑症时要谨慎。非药物干预和改用SSRI被适度地用作苯二氮卓抗焦虑药的主要治疗选择和替代品。为了确保在初级保健中安全有效地治疗未指明的焦虑症，更多的信息应该从领域专家那里提供。
