关键词: anaphylaxis children pediatric allergy polyvinylpyrrolidone povidone povidone anaphylaxis

Mesh : Humans Anaphylaxis / chemically induced diagnosis Male Child, Preschool Povidone-Iodine / adverse effects administration & dosage Anti-Infective Agents, Local / adverse effects administration & dosage Drug Hypersensitivity / diagnosis etiology Epinephrine / administration & dosage adverse effects Ophthalmic Solutions / adverse effects

来  源:   DOI:10.1089/ped.2024.0036

Abstract:
Background: Povidone, a synthetic polymer commonly used in various products such as antiseptics, cosmetics, and medications, has been associated with allergic reactions, including anaphylaxis. Despite its widespread use, cases of povidone-induced anaphylaxis, especially in children, are under-recognized. This case report aims to highlight the importance of considering povidone allergy in pediatric patients presenting with anaphylaxis. Case Presentation: We describe a 3-year-old boy who experienced anaphylaxis following the application of povidone-iodine antiseptic solution to a leg wound. He presented with generalized urticaria, angioedema, dyspnea, and cough. Prompt diagnosis and management were initiated in the emergency department. He experienced the second anaphylaxis with povidone-containing eye drops prescribed during an ophthalmology visit. Conclusions: Povidone allergy should be considered in pediatric patients presenting with anaphylaxis, especially those with idiopathic reactions or multiple drug allergies. Clinicians should emphasize patient education on label reading and the provision of adrenaline autoinjectors to prevent life-threatening reactions associated with povidone exposure.
摘要:
背景:聚维酮,一种常用于各种产品如防腐剂的合成聚合物,化妆品,和药物,与过敏反应有关,包括过敏反应.尽管它广泛使用,聚维酮引起的过敏反应,尤其是在儿童中,被低估了。本病例报告旨在强调在出现过敏反应的儿科患者中考虑聚维酮过敏的重要性。病例介绍:我们描述了一个3岁的男孩,在将聚维酮碘消毒液应用于腿部伤口后出现过敏反应。他出现了全身性荨麻疹,血管性水肿,呼吸困难,还有咳嗽.急诊部门已开始及时诊断和管理。在眼科就诊期间,他使用含聚维酮的滴眼液进行了第二次过敏反应。结论:出现过敏反应的儿科患者应考虑聚维酮过敏,特别是那些有特发性反应或多种药物过敏的人。临床医生应强调对患者进行标签阅读和提供肾上腺素自动注射器的教育,以防止与聚维酮接触相关的危及生命的反应。
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