PDF(Pubmed)
Abstract：
Toxic megacolon denotes an abrupt non-obstructive distension of the colon, accompanied by systemic signs of toxicity. Mortality rates can soar as high as 7.9%. While primarily linked with chronic bowel conditions, the incidence attributed to Clostridioides difficile has surged due to the indiscriminate use of broad-spectrum antibiotics. Surgical intervention becomes necessary in the majority of cases. Herein, we illustrate the case of a 50-year-old female presenting with episodic epigastric pain lasting 9 h, vomiting, and watery bowel movements, devoid of peritoneal irritation findings and lacking a history of chronic intestinal inflammation. Under certain circumstances, toxic megacolon may manifest atypically, underscoring the importance of conducting a comprehensive medical history and clinical assessment. Moreover, it is imperative to solicit pertinent paraclinical investigations to address the patient holistically and foster a favorable clinical outcome.
摘要：
中毒性巨结肠表示结肠突然非阻塞性扩张，伴有全身毒性症状。死亡率可高达7.9%。虽然主要与慢性肠道疾病有关，由于滥用广谱抗生素,艰难梭菌的发病率激增.在大多数情况下，手术干预是必要的。在这里，我们说明了一个50岁的女性出现持续9小时的发作性胃痛的情况，呕吐,和水汪汪的排便，没有腹膜刺激的发现，也没有慢性肠道炎症的病史。在某些情况下,有毒巨结肠可能非典型地表现出来，强调进行全面病史和临床评估的重要性。此外，必须征求相关的临床旁检查，以从整体上解决患者问题并促进良好的临床结局。
