{Reference Type}: Case Reports
{Title}: Toxic megacolon: a potentially lethal condition. Case report.
{Author}: Fabián-Méndez JJ;Torres-Salazar QL;
{Journal}: J Surg Case Rep
{Volume}: 2024
{Issue}: 6
{Year}: 2024 Jun
暂无{DOI}: 10.1093/jscr/rjae403
{Abstract}: Toxic megacolon denotes an abrupt non-obstructive distension of the colon, accompanied by systemic signs of toxicity. Mortality rates can soar as high as 7.9%. While primarily linked with chronic bowel conditions, the incidence attributed to Clostridioides difficile has surged due to the indiscriminate use of broad-spectrum antibiotics. Surgical intervention becomes necessary in the majority of cases. Herein, we illustrate the case of a 50-year-old female presenting with episodic epigastric pain lasting 9 h, vomiting, and watery bowel movements, devoid of peritoneal irritation findings and lacking a history of chronic intestinal inflammation. Under certain circumstances, toxic megacolon may manifest atypically, underscoring the importance of conducting a comprehensive medical history and clinical assessment. Moreover, it is imperative to solicit pertinent paraclinical investigations to address the patient holistically and foster a favorable clinical outcome.