METHODS: A 22-year-old woman with a history of congenital lipo-myelomeningocele surgery as an infant presented with a 6-month history of back pain. This pain gradually resulted in limb weakness, paraparesis, and loss of bladder and bowel control. An MRI showed a 6 × 5 × 3 cm spinal canal mass at the L4-S1 level. Consequently, a laminectomy was performed at the L4-L5 level to remove the intramedullary tumor. Post-surgery histopathology and immunohistochemistry confirmed the tumor as ERWT with favorable histology without any teratomatous component.
CONCLUSIONS: This report underscores the rarity of extrarenal Wilms tumor (ERWT) in adults, challenging conventional assumptions about its typical age of occurrence. It emphasizes the importance of clinical awareness regarding such uncommon cases. Moreover, the co-occurrence of spinal ERWTs and a history of spinal anomalies warrants further investigation.
方法:一名22岁女性,有先天性脂肪-脊髓膜膨出手术史,婴儿时出现6个月的背痛史。这种疼痛逐渐导致肢体无力,轻瘫,膀胱和肠道失控.MRI显示L4-S1水平有6×5×3cm的椎管肿块。因此,在L4-L5水平进行椎板切除术以切除髓内肿瘤.手术后组织病理学和免疫组织化学证实肿瘤为ERWT,组织学良好,无任何畸胎瘤成分。
结论:本报告强调了成人肾外肾母细胞瘤(ERWT)的罕见性,挑战关于其典型发生年龄的传统假设。它强调了对此类罕见病例的临床认识的重要性。此外,脊髓ERWT的同时发生和脊髓异常的病史值得进一步调查.