Abstract：
OBJECTIVE: A plasma transfusion dose should be weight-based (10-20 mL/kg), which equates to three to four units in an average-sized adult; therefore, the transfusion of single units under most circumstances is sub-therapeutic.
METHODS: This retrospective observational study examined the prevalence of single-unit plasma transfusion in adults within a 12-hospital system from 1 January 2018, to 31 December 2019.
RESULTS: During the study period, 5791 patients received plasma transfusions. The overall prevalence of single-unit plasma was 17.1% for 988 patients. The majority, 3047 (52.6%), occurred at one hospital, 2132 (36.9%) among five hospitals and 612 (10.7%) at the remaining six hospitals. Cardiac and gastrointestinal (GI)/transplant transfused 2707 (46.8%), combined respiratory, neurological, orthopaedic and congenital/dermatology/other comprised 2133 (36.9%) of the six hospitals that transfused less than 200 patients, four (66.7%) transfused single units above the overall prevalence.
CONCLUSIONS: In this hospital system, more than one in six patients received a transfusion of a single plasma unit. Six of the 12 hospitals had 89.5% of the patients who were transfused plasma. Six service lines transfused 83.7% of all patients receiving plasma. Hospitals that infrequently transfused plasma were more likely to under-dose.
METHODS: This retrospective observational study examined the prevalence of single-unit plasma transfusion in adults within a 12-hospital system from 1 January 2018, to 31 December 2019.
RESULTS: During the study period, 5791 patients received plasma transfusions. The overall prevalence of single-unit plasma was 17.1% for 988 patients. The majority, 3047 (52.6%), occurred at one hospital, 2132 (36.9%) among five hospitals and 612 (10.7%) at the remaining six hospitals. Cardiac and gastrointestinal (GI)/transplant transfused 2707 (46.8%), combined respiratory, neurological, orthopaedic and congenital/dermatology/other comprised 2133 (36.9%) of the six hospitals that transfused less than 200 patients, four (66.7%) transfused single units above the overall prevalence.
CONCLUSIONS: In this hospital system, more than one in six patients received a transfusion of a single plasma unit. Six of the 12 hospitals had 89.5% of the patients who were transfused plasma. Six service lines transfused 83.7% of all patients receiving plasma. Hospitals that infrequently transfused plasma were more likely to under-dose.
摘要：
目的：血浆输注剂量应基于体重（10-20mL/kg），这相当于一个普通成年人的三到四个单位；因此，在大多数情况下，单个单位的输血是亚治疗性的。
方法：这项回顾性观察性研究调查了2018年1月1日至2019年12月31日在12家医院系统内成人单单位血浆输注的患病率。
结果：在研究期间，5791例患者接受了血浆输血。988例患者单单位血浆的总患病率为17.1%。大多数,3047（52.6%），发生在一家医院，五家医院中有2132家(36.9%)，其余六家医院有612家(10.7%)。心脏和胃肠道（GI）/移植输血2707（46.8％），联合呼吸，神经学,骨科和先天性/皮肤病学/其他包括6家输血少于200名患者的医院中的2133家（36.9％），4例(66.7%)输血单位高于总患病率.
结论：在这个医院系统中，六分之一以上的患者接受了单一血浆单位的输血。12家医院中有6家医院有89.5％的患者输入了血浆。六个服务线输注了所有接受血浆的患者的83.7％。不经常输入血浆的医院更有可能剂量不足。
方法：这项回顾性观察性研究调查了2018年1月1日至2019年12月31日在12家医院系统内成人单单位血浆输注的患病率。
结果：在研究期间，5791例患者接受了血浆输血。988例患者单单位血浆的总患病率为17.1%。大多数,3047（52.6%），发生在一家医院，五家医院中有2132家(36.9%)，其余六家医院有612家(10.7%)。心脏和胃肠道（GI）/移植输血2707（46.8％），联合呼吸，神经学,骨科和先天性/皮肤病学/其他包括6家输血少于200名患者的医院中的2133家（36.9％），4例(66.7%)输血单位高于总患病率.
结论：在这个医院系统中，六分之一以上的患者接受了单一血浆单位的输血。12家医院中有6家医院有89.5％的患者输入了血浆。六个服务线输注了所有接受血浆的患者的83.7％。不经常输入血浆的医院更有可能剂量不足。
