关键词: Cervical spine Histiocytosis Langerhans cell histiocytosis

Mesh : Humans Histiocytosis, Langerhans-Cell / surgery pathology complications diagnosis Cervical Vertebrae / surgery pathology diagnostic imaging Male Young Adult Adult

来  源:   DOI:10.12688/f1000research.139360.1   PDF(Pubmed)

Abstract:
Langerhans Cell Histiocytosis (LCH) is a typically benign disorder that affects infants predominately, with adult occurrence being uncommon. We discuss the case of a 22-year-old guy who visited our clinic complaining of three months of acute nape pain and upper limb radiculopathy. Notably, the patient had no history of trauma, fall injuries, or tuberculosis. Radiological tests identified a single osteolytic lesion within the C3 vertebral body. The lesion was removed, an anterior C3 corpectomy and discectomy were performed, and the patient\'s spine was reconstructed with a titanium cage and plating. The patient\'s nape discomfort and radiculopathy vanished almost instantly after surgery. A definitive diagnosis of LCH was confirmed through histological examination. This case report illustrates the unusual and uncommon occurrence of LCH at the C3 vertebral body, for which fusion surgery was the only viable therapeutic option. The patient\'s recovery from radiating pain following the surgical procedure demonstrates the effectiveness of the intervention. LCH in the cervical spine is rather rare, but it is nevertheless important to be aware of the possibility of developing it.
摘要:
朗格汉斯细胞组织细胞增生症(LCH)是一种典型的良性疾病,主要影响婴儿,成人的发生并不常见。我们讨论了一个22岁的男子的案例,他去了我们的诊所,抱怨三个月的急性颈痛和上肢神经根病。值得注意的是,病人没有外伤史,摔伤,或肺结核。放射学测试确定了C3椎体内的单个溶骨性病变。病灶被切除了,进行了前C3椎体切除术和椎间盘切除术,病人的脊柱用钛笼和钢板重建。手术后患者的颈项不适和神经根病几乎立即消失。通过组织学检查证实了LCH的明确诊断。此病例报告说明了C3椎体LCH的异常和罕见发生,融合手术是唯一可行的治疗选择.手术后患者从放射性疼痛中恢复,证明了干预的有效性。颈椎中的LCH相当罕见,但是,重要的是要意识到开发它的可能性。
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