关键词: Camellia sinensis linn INA score green tea extract stretch mark striae distensae

Mesh : Humans Female Plant Extracts / therapeutic use pharmacology Striae Distensae / drug therapy Adult Adolescent Camellia sinensis / chemistry Young Adult Tea / chemistry Male Treatment Outcome Skin Cream / therapeutic use

来  源:   DOI:10.12688/f1000research.142199.1   PDF(Pubmed)

Abstract:
UNASSIGNED: Striae distensae (SD) is a skin condition that frequently causes dermatological consultations and although asymptomatic, it may can cause itch and burning sensation. Green tea extract contains polyphenol, including flavanol, flavandiol, flavonoid, phenolic acid, amino acids and minerals which play a role in the repair of stretch marks through anti-inflammatory mechanism, increase collagen production, fibroblast proliferation, and skin hydration.
UNASSIGNED: To determine the efficacy of green tea extract cream on striae distensae.
UNASSIGNED: This is a pre-experimental clinical trial with a pretest-posttest design on 36 subjects with striae distensae. Diagnosis establishes through history taking and clinical evaluation. Imam Nelva Alviera (INA) score was used as SD severity before and after the application of the 3% green tea extract cream carried out at weeks 0, 2, 4, 6, and 8. Side effects and subjects\' satisfaction were also recorded. Cochran test was carried out to see the difference before and after treatment, with a p-value <0.05 considered significant.
UNASSIGNED: Majority of study subjects were 18-25 years (77.8%), had history of pregnancy (75%), had a history of menarche at the age of 12 years (27.8%) and all subjects had striae alba. There was significant decrement in INA score for striae distensae (p<0.001) after eight weeks administration of 3% green tea extract cream. Clinical improvement and no side effects were also noted. All subjects were satisfied.
UNASSIGNED: The use of 3% green tea extract cream can improve the appearance of SD.
摘要:
鱼纹(SD)是一种皮肤疾病,经常引起皮肤病咨询,尽管无症状,它可能会引起瘙痒和灼烧感。绿茶提取物含有多酚,包括黄烷醇,黄二醇,类黄酮,酚酸,氨基酸和矿物质通过抗炎机制在妊娠纹修复中发挥作用,增加胶原蛋白的产生,成纤维细胞增殖,和皮肤水合作用。
确定绿茶提取物乳膏对条纹的功效。
这是一项实验前的临床试验,对36名患有纹状体的受试者进行了前测-后测设计。诊断通过病史记录和临床评估建立。ImamNelvaAlviera(INA)评分用作在第0、2、4、6和8周进行的施用3%绿茶提取物乳膏之前和之后的SD严重性。还记录了副作用和受试者的满意度。进行Cochran试验,观察治疗前后的差异,p值<0.05被认为是显著的。
大多数研究对象为18-25岁(77.8%),有妊娠史(75%),在12岁时有初潮史(27.8%),所有受试者都有白纹。在施用3%绿茶提取物乳膏八周后,条纹的INA评分显着下降(p<0.001)。还注意到临床改善和无副作用。所有受试者都很满意。
使用3%的绿茶提取物奶油可以改善SD的外观。
公众号