PDF(Pubmed)
Abstract：
BACKGROUND: Resistance exercise training (RET) can increase muscle mass and strength, and this adaptation is optimized when dietary protein is consumed to enhance muscle protein synthesis. Dairy milk has been endorsed for this purpose; however, allergy and lactose intolerance affect two-thirds of the global population making dairy milk unsuitable for many. Plant-based alternatives such as soy milk have gained popularity and exhibit comparable protein content. However, concerns regarding soy phytoestrogens potentially influencing circulating sex hormones and diminishing the anabolic response to RET have been raised. This study therefore aimed to assess the acute effects of dairy and soy milk consumption on circulating sex hormones (total, free testosterone, free testosterone percentage, total estrogen, progesterone, and sex hormone binding globulin) after RET.
METHODS: Six male participants were recruited for a double-blinded, randomized crossover study with either dairy or soy milk provided post RET. Venous samples were collected before and after milk consumption across seven timepoints (0-120 minutes) where circulating sex hormones were analyzed. Two-way ANOVA analyses were applied for repeated measures for each hormone. The area under the curve (AUC) was also calculated between dairy and soy milk. Significance was set at p<0.05.
RESULTS: No significant differences were observed in acute circulating serum for free (p=0.95), % free (p=0.56), and total testosterone (p=0.88), progesterone (p=0.67), or estrogen (p=0.21) between milk conditions. Likewise, no significant differences in AUC were observed between any hormones.
CONCLUSIONS: These findings suggest that consumption of dairy milk and soy milk have comparable acute effects on circulating sex hormones following RET. Further investigations with expanded sample sizes are needed to strengthen and broaden these initial findings.
METHODS: Six male participants were recruited for a double-blinded, randomized crossover study with either dairy or soy milk provided post RET. Venous samples were collected before and after milk consumption across seven timepoints (0-120 minutes) where circulating sex hormones were analyzed. Two-way ANOVA analyses were applied for repeated measures for each hormone. The area under the curve (AUC) was also calculated between dairy and soy milk. Significance was set at p<0.05.
RESULTS: No significant differences were observed in acute circulating serum for free (p=0.95), % free (p=0.56), and total testosterone (p=0.88), progesterone (p=0.67), or estrogen (p=0.21) between milk conditions. Likewise, no significant differences in AUC were observed between any hormones.
CONCLUSIONS: These findings suggest that consumption of dairy milk and soy milk have comparable acute effects on circulating sex hormones following RET. Further investigations with expanded sample sizes are needed to strengthen and broaden these initial findings.
摘要：
背景：阻力运动训练（RET）可以增加肌肉质量和力量，当膳食蛋白质被消耗以增强肌肉蛋白质合成时，这种适应被优化。牛奶已被认可用于此目的；然而，过敏和乳糖不耐受影响全球三分之二的人口，使得牛奶不适合许多人。基于植物的替代品，如豆奶，已经越来越受欢迎，并表现出可比的蛋白质含量。然而,关于大豆植物雌激素可能影响循环性激素和减少对RET的合成代谢反应的担忧已经引起。因此，这项研究旨在评估乳制品和豆浆消费对循环性激素的急性影响（总计，游离的睾酮,游离睾酮百分比,总雌激素，黄体酮,和性激素结合球蛋白）在RET后。
方法：招募六名男性参与者进行双盲，RET后提供了乳制品或豆浆的随机交叉研究。在分析循环性激素的七个时间点(0-120分钟)内,在牛奶消耗之前和之后收集静脉样品。对每种激素的重复测量应用双向ANOVA分析。还计算了乳品和豆奶之间的曲线下面积(AUC)。显著性设定为p<0.05。
结果：在无急性循环血清中没有观察到显著差异（p=0.95），%游离(p=0.56)，和总睾酮（p=0.88），孕酮（p=0.67），或雌激素（p=0.21）之间的牛奶条件。同样，任何激素之间的AUC均未观察到显着差异。
结论：这些研究结果表明，食用牛奶和豆浆对RET后循环性激素具有相当的急性影响。需要扩大样本量的进一步调查，以加强和扩大这些初步发现。
方法：招募六名男性参与者进行双盲，RET后提供了乳制品或豆浆的随机交叉研究。在分析循环性激素的七个时间点(0-120分钟)内,在牛奶消耗之前和之后收集静脉样品。对每种激素的重复测量应用双向ANOVA分析。还计算了乳品和豆奶之间的曲线下面积(AUC)。显著性设定为p<0.05。
结果：在无急性循环血清中没有观察到显著差异（p=0.95），%游离(p=0.56)，和总睾酮（p=0.88），孕酮（p=0.67），或雌激素（p=0.21）之间的牛奶条件。同样，任何激素之间的AUC均未观察到显着差异。
结论：这些研究结果表明，食用牛奶和豆浆对RET后循环性激素具有相当的急性影响。需要扩大样本量的进一步调查，以加强和扩大这些初步发现。
