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Abstract：
In this review article, a perspective on the immobilization of various hydrolytic enzymes onto magnetic nanoparticles for synthetic organic chemistry applications is presented. After a first part giving short overview on nanomagnetism and highlighting advantages and disadvantages of immobilizing enzymes on magnetic nanoparticles (MNPs), the most important hydrolytic enzymes and their applications were summarized. A section reviewing the immobilization techniques with a particular focus on supporting enzymes on MNPs introduces the reader to the final chapter describing synthetic organic chemistry applications of small molecules (flavour esters) and polymers (polyesters and polyamides). Finally, the conclusion and perspective section gives the author\'s personal view on further research discussing the new idea of a synergistic rational design of the magnetic and biocatalytic component to produce novel magnetic nano-architectures.
摘要：
在这篇评论文章中，提出了将各种水解酶固定在磁性纳米颗粒上用于合成有机化学应用的观点。在第一部分简要概述了纳米磁性并突出了磁性纳米颗粒（MNPs）上固定酶的优缺点之后，综述了最重要的水解酶及其应用。回顾固定化技术的部分，特别着重于支持MNPs上的酶，向读者介绍了最后一章，描述了小分子（调味剂酯）和聚合物（聚酯和聚酰胺）的合成有机化学应用。最后,结论和观点部分给出了作者对进一步研究的个人观点，讨论了磁性和生物催化组件协同合理设计以生产新型磁性纳米结构的新思路。
