关键词: Bifid uvula Bony notch Calnan’s triad Submucous cleft palate Velopharyngeal insufficiency Zona pellucida

Mesh : Humans Velopharyngeal Insufficiency / etiology physiopathology Cleft Palate / complications surgery Female Male Retrospective Studies Child Adolescent Child, Preschool Adult Young Adult Uvula / abnormalities

来  源:   DOI:10.1016/j.bjps.2024.05.006

Abstract:
BACKGROUND: Submucous cleft palate (SMCP) is a congenital anomaly characterized by the presence of Calnan\'s triad. However, in clinical practice, it is common for individuals to exhibit one or two anatomical abnormalities within the triad. Furthermore, the definition of SMCP has been diverse and ambiguous in literature. Therefore, this study aimed to analyze the correlation between anatomical abnormalities and development of velopharyngeal insufficiency (VPI).
METHODS: We conducted a retrospective analysis of 99 patients referred to our clinic for speech issues or anatomical abnormalities identified during routine oral examinations from January 2012 to June 2023. A single surgeon performed all physical examinations. We evaluated the presence of bony notch, zona pellucida, and bifid uvula, assigned a score to each abnormality, and analyzed their correlation with VPI. The correlation of each of the abnormalities with VPI development was examined, along with the relationship between the number of abnormalities and VPI.
RESULTS: Among the 99 patients, 27 were diagnosed with VPI. Only the bony notch had a significant correlation with VPI development. The incidence of VPI tended to increase with the presence of more anatomical abnormalities. VPI occurred in approximately 40% of patients exhibiting all three anatomical abnormalities.
CONCLUSIONS: The study findings highlight the importance of meticulous intraoral examinations in patients with SMCP and careful monitoring of patients with a bony notch or two or more anatomical abnormalities.
摘要:
背景:粘膜下腭裂(SMCP)是一种先天性异常,其特征是存在Calnan三联征。然而,在临床实践中,对于个人来说,在三合会中表现出一个或两个解剖异常是很常见的。此外,SMCP的定义在文献中一直是多样和模糊的。因此,本研究旨在分析解剖学异常与咽喉功能不全(VPI)发生的相关性。
方法:我们对2012年1月至2023年6月因常规口腔检查中发现的语音问题或解剖学异常而转诊到我们诊所的99例患者进行了回顾性分析。一名外科医生进行了所有体检。我们评估了骨性缺口的存在,透明带,和双歧小舌,给每个异常分配一个分数,并分析了它们与VPI的相关性。检查了每种异常与VPI发展的相关性,随着异常数量与VPI的关系。
结果:在99名患者中,27例确诊为VPI。只有骨性缺口与VPI发育有显著相关性。随着更多解剖异常的存在,VPI的发生率趋于增加。VPI发生在所有三种解剖异常的患者中约40%。
结论:研究结果强调了对SMCP患者进行细致的口内检查以及对有骨性切迹或两个或两个以上解剖异常的患者进行仔细监测的重要性。
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