Abstract：
OBJECTIVE: To systematically evaluate the current status of apathy in dementia patients and its associated factors.
METHODS: We searched Chinese and English databases to collect studies on the associated factors of apathy in patients with dementia from inception to March 14, 2023. Two researchers independently screened the literature, evaluated the quality, and extracted the data RESULTS: A total of 20 studies were included, and the incidence of apathy in patients with dementia ranged from 21 % to 90 %. According to the model of apathy proposed by Massimo in 2018, the associated factors were divided into individual factors for dementia patients, caregiver factors, and environmental factors. The individual factors of apathy in patients with dementia mainly include demographic characteristics, the severity of cognitive impairment, a combination of other behavioral and psychological symptoms of dementia, acute medical problems or adverse drug reactions, unmet needs, and malnutrition. Caregiver factors mainly include emotional expressions of hostility or criticism towards dementia patients and caregivers\' expectations for a better life in the future. Environmental factors mainly include too high or too low stimulation and a lack of daytime activities CONCLUSIONS: Existing studies have shown that the incidence of apathy in dementia patients is high and is affected by multi-dimensional factors. There are more studies on individual factors in dementia patients and fewer studies on caregivers and environmental factors. In the future, a large number of high-quality studies are needed to demonstrate the mechanism of apathy in dementia patients and to find more related factors.
METHODS: We searched Chinese and English databases to collect studies on the associated factors of apathy in patients with dementia from inception to March 14, 2023. Two researchers independently screened the literature, evaluated the quality, and extracted the data RESULTS: A total of 20 studies were included, and the incidence of apathy in patients with dementia ranged from 21 % to 90 %. According to the model of apathy proposed by Massimo in 2018, the associated factors were divided into individual factors for dementia patients, caregiver factors, and environmental factors. The individual factors of apathy in patients with dementia mainly include demographic characteristics, the severity of cognitive impairment, a combination of other behavioral and psychological symptoms of dementia, acute medical problems or adverse drug reactions, unmet needs, and malnutrition. Caregiver factors mainly include emotional expressions of hostility or criticism towards dementia patients and caregivers\' expectations for a better life in the future. Environmental factors mainly include too high or too low stimulation and a lack of daytime activities CONCLUSIONS: Existing studies have shown that the incidence of apathy in dementia patients is high and is affected by multi-dimensional factors. There are more studies on individual factors in dementia patients and fewer studies on caregivers and environmental factors. In the future, a large number of high-quality studies are needed to demonstrate the mechanism of apathy in dementia patients and to find more related factors.
摘要：
目的：系统评价痴呆患者情感淡漠的现状及其相关因素。
方法：我们检索了中文和英文数据库，收集了从发病到2023年3月14日痴呆患者冷漠相关因素的研究。两名研究人员独立筛选了文献，评估质量，结果:共纳入20项研究,痴呆患者的冷漠发生率为21%至90%。根据Massimo在2018年提出的冷漠模型，将相关因素分为痴呆患者的个体因素，照顾者因素，和环境因素。痴呆患者冷漠的个体因素主要包括人口学特征,认知障碍的严重程度，痴呆症的其他行为和心理症状的组合，急性医疗问题或药物不良反应，未满足的需求，和营养不良。照顾者因素主要包括对痴呆症患者和照顾者对未来美好生活的期望的敌意或批评的情绪表达。环境因素主要包括过高或过低的刺激和缺乏日间活动。结论：现有研究表明，痴呆患者冷漠的发生率较高，并受到多维因素的影响。对痴呆患者个体因素的研究较多，对照顾者和环境因素的研究较少。在未来,需要大量高质量的研究来证明痴呆患者冷漠的机制，并找到更多的相关因素。
方法：我们检索了中文和英文数据库，收集了从发病到2023年3月14日痴呆患者冷漠相关因素的研究。两名研究人员独立筛选了文献，评估质量，结果:共纳入20项研究,痴呆患者的冷漠发生率为21%至90%。根据Massimo在2018年提出的冷漠模型，将相关因素分为痴呆患者的个体因素，照顾者因素，和环境因素。痴呆患者冷漠的个体因素主要包括人口学特征,认知障碍的严重程度，痴呆症的其他行为和心理症状的组合，急性医疗问题或药物不良反应，未满足的需求，和营养不良。照顾者因素主要包括对痴呆症患者和照顾者对未来美好生活的期望的敌意或批评的情绪表达。环境因素主要包括过高或过低的刺激和缺乏日间活动。结论：现有研究表明，痴呆患者冷漠的发生率较高，并受到多维因素的影响。对痴呆患者个体因素的研究较多，对照顾者和环境因素的研究较少。在未来,需要大量高质量的研究来证明痴呆患者冷漠的机制，并找到更多的相关因素。
