Mesh : Humans Keratoconus / physiopathology metabolism drug therapy surgery Corneal Stroma / metabolism surgery Cross-Linking Reagents / therapeutic use Visual Acuity / physiology Adult Male Female Prosthesis Implantation Photosensitizing Agents / therapeutic use Retrospective Studies Corneal Topography Young Adult Prostheses and Implants Refraction, Ocular / physiology Collagen / metabolism Corneal Pachymetry Riboflavin / therapeutic use Photochemotherapy / methods Adolescent Ultraviolet Rays Corneal Transplantation / methods Middle Aged Corneal Cross-Linking

来  源:   DOI:10.3928/1081597X-20240501-01

Abstract:
UNASSIGNED: To compare the effects of corneal allogenic intrastromal ring segment (CAIRS) implantation on topographical measurements and visual outcomes of patients with keratoconus with and without corneal cross-linking (CXL) prior to the time of implantation.
UNASSIGNED: Sixty-seven eyes with corneal allograft intrastromal ring segment implantation (KeraNatural; Lions VisionGift) due to advanced keratoconus were included in the study. Thirty-seven eyes had no CXL and 30 eyes had had CXL before being referred to the authors. The changes in spherical equivalent (SE), uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), steep keratometry (K1), flat keratometry (K2), mean keratometry (Kmean), maximum keratometry (Kmax), and thinnest pachymetry were retrospectively analyzed 6 months after the implantation.
UNASSIGNED: The median age was 29 years in the CXL group and 24.0 years in the non-CXL group (P > .05), respectively. All topographical and visual parameters before implantation were similar in both groups (P > .05 for all parameters). At 6 months, CDVA, K1, and Kmean showed higher improvement in the non-CXL group than the CXL group (P = .030, .018, and .039, respectively).
UNASSIGNED: CAIRS surgery has a flattening effect on both the corneas with and without CXL. The cornea with prior CXL treatment had less flattening effect due to the stiffening effect of prior CXL. [J Refract Surg. 2024;40(6):e392-e397.].
摘要:
比较角膜同种异体真皮内环段(CAIRS)植入对植入前有和没有角膜交联(CXL)的圆锥角膜患者的地形测量和视觉结果的影响。
67只眼因圆锥角膜晚期而植入同种异体角膜基质环段(KeraNatural;LionsVisionGift)。在提交给作者之前,有37只眼没有CXL,有30只眼有CXL。球面当量(SE)的变化,非矫正视力(UDVA),矫正视力(CDVA),陡峭角膜曲率术(K1),平面角膜曲率测量(K2),平均角膜曲率(Kmean),最大角膜曲率测量(Kmax),植入后6个月,回顾性分析最薄的厚度。
CXL组的中位年龄为29岁,非CXL组的中位年龄为24.0岁(P>0.05),分别。植入前两组的所有地形和视觉参数相似(所有参数P>.05)。6个月时,CDVA,与CXL组相比,非CXL组的K1和Kmean显示出更高的改善(分别为P=.030,.018和.039)。
CAIRS手术对具有和不具有CXL的角膜均具有展平作用。由于先前CXL的硬化效应,具有先前CXL治疗的角膜具有较小的展平效应。[JRefractSurg.2024;40(6):e392-e397。].
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