Abstract：
Fungal keratitis (FK) is a severe ocular condition resulting from corneal infection that is prevalent in tropical countries, particularly in developing regions of Asia and Africa. Factors like corneal lens misuse, inappropriate steroid use, and diagnostic challenges have provoked the epidemic. FK causes significant vision impairment, scarring, and ocular deformities. Accurate pathological diagnosis is crucial for effective therapeutic intervention. Topical antifungal therapy with surface healing medications proves effective in preventing fungal-borne ulcers. Managing FK requires a comprehensive understanding of fungal pathogenesis, guiding formulation strategies and preventive measures to curb global ocular blindness. This review provides in-depth insights into FK, covering etiology, epidemiology, pathogenesis, therapeutic interventions, antifungal resistance, limitations, prevention, and future perspectives on ocular surface disease management.
摘要：
真菌性角膜炎（FK）是一种由角膜感染引起的严重眼部疾病，在热带国家很普遍，特别是在亚洲和非洲的发展中地区。角膜晶状体误用等因素，不适当的类固醇使用，诊断挑战引发了这一流行病。FK导致严重的视力损害，疤痕,和眼畸形。准确的病理诊断对于有效的治疗干预至关重要。表面愈合药物的局部抗真菌治疗证明可有效预防真菌传播的溃疡。管理FK需要对真菌发病机理有全面的了解，指导制定策略和预防措施，以遏制全球眼盲。这篇评论提供了对FK的深入见解，涵盖病因，流行病学,发病机制，治疗性干预措施,抗真菌耐药性，局限性,预防,以及对眼表疾病管理的未来展望。
