PDF(Pubmed)
Abstract：
Addison\'s disease is a rare, autoimmune condition leading to destruction of the adrenal gland. Autoimmune conditions are known to commonly co-occur. When Addison\'s disease presents in the setting of autoimmune thyroid disease and/or type 1 diabetes, this condition is termed autoimmune polyendocrine syndrome type II, a rare endocrinopathy found in roughly 1.4-4.5 per 100,000 individuals. Here, we describe a clinical case presenting with hypotension refractory to fluid resuscitation and electrolyte derangements later diagnosed as autoimmune polyendocrine syndrome type II.
CONCLUSIONS: Primary adrenal insufficiency may present clinically as shock refractory to fluid resuscitation.Autoimmune polyglandular syndrome type 2 is a rare autoimmune condition occurring in 1.5-4.5 per 100,000 individuals.The presence of an underlying autoimmune condition should raise suspicion for multiple concurrent autoimmune conditions.
CONCLUSIONS: Primary adrenal insufficiency may present clinically as shock refractory to fluid resuscitation.Autoimmune polyglandular syndrome type 2 is a rare autoimmune condition occurring in 1.5-4.5 per 100,000 individuals.The presence of an underlying autoimmune condition should raise suspicion for multiple concurrent autoimmune conditions.
摘要：
艾迪生的病是一种罕见的,导致肾上腺破坏的自身免疫性疾病。已知自身免疫病症通常共同发生。当Addison病出现在自身免疫性甲状腺疾病和/或1型糖尿病的背景下，这种情况被称为II型自身免疫性多内分泌综合征，一种罕见的内分泌病，每10万人中大约有1.4-4.5人。这里,我们描述了一个临床病例，表现为液体复苏和电解质紊乱难治性低血压，后来被诊断为II型自身免疫性多内分泌综合征。
结论：原发性肾上腺功能不全在临床上可能表现为液体复苏难治的休克。2型自身免疫性多腺综合征是一种罕见的自身免疫性疾病，每100,000人中有1.5-4.5人。潜在自身免疫性疾病的存在应引起对多种并发自身免疫性疾病的怀疑。
结论：原发性肾上腺功能不全在临床上可能表现为液体复苏难治的休克。2型自身免疫性多腺综合征是一种罕见的自身免疫性疾病，每100,000人中有1.5-4.5人。潜在自身免疫性疾病的存在应引起对多种并发自身免疫性疾病的怀疑。
