{Reference Type}: Journal Article
{Title}: A Silent Cause of Shock: Autoimmune Polyglandular Syndromes.
{Author}: Colantonio MA;Hartzell M;Shannon B;Iyer A;
{Journal}: Eur J Case Rep Intern Med
{Volume}: 11
{Issue}: 6
{Year}: 2024
暂无{DOI}: 10.12890/2024_004627
{Abstract}: Addison's disease is a rare, autoimmune condition leading to destruction of the adrenal gland. Autoimmune conditions are known to commonly co-occur. When Addison's disease presents in the setting of autoimmune thyroid disease and/or type 1 diabetes, this condition is termed autoimmune polyendocrine syndrome type II, a rare endocrinopathy found in roughly 1.4-4.5 per 100,000 individuals. Here, we describe a clinical case presenting with hypotension refractory to fluid resuscitation and electrolyte derangements later diagnosed as autoimmune polyendocrine syndrome type II.<BR><B>CONCLUSIONS: </B>Primary adrenal insufficiency may present clinically as shock refractory to fluid resuscitation.Autoimmune polyglandular syndrome type 2 is a rare autoimmune condition occurring in 1.5-4.5 per 100,000 individuals.The presence of an underlying autoimmune condition should raise suspicion for multiple concurrent autoimmune conditions.