关键词: fenbendazole formaldehyde ivermectin levamisole mebendazole

来  源:   DOI:10.17221/66/2022-VETMED   PDF(Pubmed)

Abstract:
The study aimed to assess the effects of a therapeutic bath of five different antiparasitic drugs, in different baths and durations: fenbendazole (25 mg l-1, 12 h and 2 × 12 h), formaldehyde (0.17 ml l-1, 15 min), ivermectin (0.031 mg l-1, 1 h), mebendazole (1 mg l-1, 12 h) and levamisole (50 mg l-1, 2 h and 3 × 1 h) on the reduction on the intensity and prevalence of a monogenean infection (Dactylogyrus anchoratus) in juvenile carp. The best effect on reducing the parasite number was achieved with the bath in formaldehyde (0.17 ml l-1, 15 min) and fenbendazole (25 mg l-1, 2 × 12 h with 24 h break), where the infection was reduced by more than 90%. Registered veterinary medicinal products (VMPs) with the active substance of fenbendazole can successfully replace the use of unregistered formaldehyde in the treatment of monogenean infections.
摘要:
该研究旨在评估五种不同抗寄生虫药物的治疗浴的效果,在不同的浴和持续时间:芬苯达唑(25mgl-1、12h和2×12h),甲醛(0.17mll-1,15分钟),伊维菌素(0.031mgl-1,1小时),甲苯咪唑(1mgl-1,12h)和左旋咪唑(50mgl-1,2h和3×1h)降低了幼鱼单基因感染(Dactylogyrusanchoratus)的强度和患病率。用甲醛浴(0.17mll-1,15分钟)和芬苯达唑(25mgl-1,2×12小时,24小时中断)达到了降低寄生虫数量的最佳效果,感染减少了90%以上。具有芬苯达唑活性物质的注册兽药(VMPs)可以成功替代未注册的甲醛用于治疗单基因感染。
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