UNASSIGNED: In this cross-sectional study, we gathered pathology reports of histological samples of adult brain tumors. The tissue sample of brain tumors were examined histologically by a pathologist. The magnetic resonance imaging data of these patients were interpreted by a neuroradiologist. The measured ADC values and ADC ratios were calculated. Standard mean ADC values were expressed as 10- 6 mm2/s. The findings were compared according to the histological diagnosis of each tumor.
UNASSIGNED: Sixty-eight patients were included in the study: 34 (50%) were male, and 34 (50%) were female. The average age of the patients was 51.69 + 16.40 years. In the examination of tumor type, 16 (23.5%) were astrocytoma, 9 (13.2%) were oligodendroglioma, 20 (29.4%) were glioblastoma, 4 (5.9%) were medulloblastoma, and 19 (27.9%) were metastatic tumors. the average value of ADC was statistically significantly different according to the pathological type of tumor (p < 0.001). The two-by-two comparison of average ADC among tumor types revealed significant differences, except for oligodendroglioma and glioblastoma (p-value = 0.87) and glioblastoma and medulloblastoma (p-value = 0.347). The average value of ADC and ADC ratio was statistically significantly different according to the pathological grade of the tumor (p < 0.001). In the two-by-two comparison of average ADC between all pathological grades of the tumor showed a significance difference except for Grade I and Grade II (p-value = 0.355). The mean value of ADC and ADC ratio for glioblastoma and metastatic tumors showed no significant difference.
UNASSIGNED: The assessment of brain tumor grade through ADC examination will help to estimate prognosis and devising suitable therapeutic strategies.
■在这项横断面研究中,我们收集了成人脑肿瘤的组织学样本的病理报告。病理学家对脑肿瘤的组织样本进行了组织学检查。这些患者的磁共振成像数据由神经放射学家解释。计算测得的ADC值和ADC比率。标准平均ADC值表示为10-6mm2/s。根据每个肿瘤的组织学诊断进行比较。
■68名患者被纳入研究:34名(50%)为男性,34(50%)为女性。患者平均年龄为51.69±16.40岁。在肿瘤类型的检查中,16例(23.5%)为星形细胞瘤,9例(13.2%)为少突胶质细胞瘤,20(29.4%)是胶质母细胞瘤,4例(5.9%)为髓母细胞瘤,转移性肿瘤19例(27.9%)。ADC值的平均值根据肿瘤的病理类型差异有统计学意义(p<0.001)。肿瘤类型之间的平均ADC的两两比较显示了显着差异,除了少突胶质细胞瘤和胶质母细胞瘤(p值=0.87)和胶质母细胞瘤和髓母细胞瘤(p值=0.347)。根据肿瘤的病理分级,ADC值和ADC比值的平均值有统计学差异(p<0.001)。在肿瘤的所有病理等级之间的平均ADC的两两比较中,除I级和II级(p值=0.355)外,显示出显着性差异。胶质母细胞瘤和转移性肿瘤的ADC平均值和ADC比值无明显差异。
■通过ADC检查评估脑肿瘤分级将有助于评估预后和制定合适的治疗策略。