PDF(Pubmed)
Abstract：
Patterned hair loss (PHL) is a severe hair condition that affects both sexes. Mesotherapy is a treatment that involves microinjecting medications and/or vitamins into the middle layer of the skin. Mesotherapy reduces systemic adverse effects by delivering drugs directly to the hair follicle, increasing local bioavailability while lowering systemic exposure. Local side effects and reactions may develop due to mesotherapy. This study systematically evaluated the safety and efficacy of mesotherapy to minoxidil 5%, as well as addressing its limitations, dosing, and technique, with the intent of providing valuable trials and insights for clinicians and patients considering mesotherapy for improved androgenetic alopecia (AGA) outcomes. The literature search carried out by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria yielded 11 relevant studies from an initial pool of 18 articles. These studies covered various aspects of the role of mesotherapy and minoxidil in AGA, including techniques, complications, limitations, and outcomes. In conclusion, available trials and research on mesotherapy and minoxidil demonstrated excellent statistical significance and a high patient satisfaction rate, with the exception of two publications that took into account certain uncommon adverse effects of mesotherapy. However, recent research suggests that a mesotherapy method for alopecia with a low risk of side effects is effective.
摘要：
图案脱发（PHL）是一种严重的头发状况，影响两性。美速疗法是一种涉及将药物和/或维生素微注射到皮肤中间层的治疗。美速疗法通过将药物直接输送到毛囊来减少全身不良反应，增加局部生物利用度，同时降低全身暴露。局部副作用和反应可能由于美体疗法而发展。这项研究系统地评估了美甲疗法对5％米诺地尔的安全性和有效性，以及解决其局限性，给药,和技术，目的是为临床医生和患者提供有价值的试验和见解，这些临床医生和患者考虑进行中胚层治疗以改善雄激素性脱发（AGA）结局。通过系统审查和荟萃分析（PRISMA）标准的首选报告项目进行的文献检索从最初的18篇文章中获得了11项相关研究。这些研究涵盖了美塑疗法和米诺地尔在AGA中的作用的各个方面，包括技术，并发症,局限性,和结果。总之,现有的试验和研究中的美体疗法和米诺地尔证明了极好的统计意义和较高的患者满意度，除了两个出版物考虑了某些不常见的美体疗法的不良反应.然而,最近的研究表明，一种副作用风险低的治疗脱发的方法是有效的。
