关键词: non-metastatic renal cell carcinoma perioperative blood transfusion prognosis radical nephrectomy

Mesh : Humans Carcinoma, Renal Cell / surgery Kidney Neoplasms / surgery pathology mortality Male Female Retrospective Studies Middle Aged Nephrectomy / methods Prognosis Blood Transfusion / statistics & numerical data Aged Perioperative Care

来  源:   DOI:10.56434/j.arch.esp.urol.20247704.56

Abstract:
OBJECTIVE: Advancements in medical science have improved non-metastatic renal cell carcinoma (NM-RCC) treatment strategies, but long-term survival is influenced by various factors, including perioperative blood transfusion. This study aims to analyse prognostic factors in patients with NM-RCC after radical nephrectomy.
METHODS: From January 2018 to December 2021, a total of 132 patients with NM-RCC after radical nephrectomy were studied. According to 2-year follow-up data, the patients were categorised into case (with poor outcomes, including pneumothorax, renal issues, recurrence or death) and control groups. Data on demographics, clinical characteristics and perioperative blood transfusion were collected, and key prognostic factors were identified through logistic regression.
RESULTS: A total of 32 patients with poor prognosis were included in the case group, accounting for 24.24% (32/132), and 100 patients without poor prognosis were included in the control group, accounting for 75.76% (100/132). Tumour stage, tumour size and perioperative blood transfusion were all risk factors for the prognosis of patients, and odds ratio (OR) >1. The above indicators had high predictive value for the prognosis of patients after surgery.
CONCLUSIONS: The prognostic factors of patients with NM-RCC after radical nephrectomy include tumour stage, tumour size and perioperative blood transfusion, and each factor had predictive value.
摘要:
目的:医学科学的进步改善了非转移性肾细胞癌(NM-RCC)的治疗策略,但是长期生存受到各种因素的影响,包括围手术期输血。本研究旨在分析根治性肾切除术后NM-RCC患者的预后因素。
方法:2018年1月至2021年12月,共132例NM-RCC患者行根治性肾切除术。根据2年的随访数据,患者被分类为病例(结果较差,包括气胸,肾脏问题,复发或死亡)和对照组。人口统计数据,收集临床特点及围手术期输血,并通过logistic回归分析确定关键预后因素。
结果:共32例预后不良的患者纳入病例组,占24.24%(32/132),100例预后不良的患者纳入对照组,占75.76%(100/132)。肿瘤阶段,肿瘤大小和围手术期输血都是影响患者预后的危险因素,和比值比(OR)>1。上述指标对术后患者的预后具有较高的预测价值。
结论:NM-RCC患者根治性肾切除术后的预后因素包括肿瘤分期,肿瘤大小和围手术期输血,每个因素都有预测价值。
公众号