Abstract：
Residential greenness is considered beneficial to human health, and its association with respiratory function has been found in previous studies. However, its link with pneumonia remains unclear. To explore the association of residential greenness with incident pneumonia, we conducted a prospective cohort study based on participants of the UK Biobank, followed from 2006 to 2010 to the end of 2019. Residential greenness was measured by Normalized Difference Vegetation Index (NDVI) within 500 m and 1000 m buffer. Cox proportional hazard models were conducted to assess the association, and restricted cubic spline models were also constructed to estimate their exposure-response relationship. Results demonstrate that residential greenness was negatively related to the risk of incident pneumonia. An interquartile (IQR) increase in NDVI 500-m buffer was associated with 4 % [HR (95 % CI) =0.96 (0.94, 0.97), P < 0.001] lower risk of incident pneumonia. Compared to the lowest greenness quartile (Q1), the highest quartile (Q4) had a lower risk of incident pneumonia, with the HR (95 % CI) estimated to be 0.91 (0.87, 0.95) (P values <0.001). Analyses based on NDVI 1000-m buffer obtained similar results. Furthermore, a significant effect of modifications by age and income on the linkage between residential greenness and incident pneumonia was found. These findings propose a potential effective prevention of incident pneumonia and provide the scientific basis for promoting the construction of residential greenness.
摘要：
住宅绿色被认为对人体健康有益，在以前的研究中已经发现了它与呼吸功能的关联。然而,它与肺炎的联系仍不清楚。探讨住宅绿化与突发肺炎的关系，我们基于英国生物银行的参与者进行了一项前瞻性队列研究，继2006年至2010年至2019年底。在500m和1000m缓冲区内，通过归一化植被指数（NDVI）测量了住宅的绿色。Cox比例风险模型进行评估的关联，并建立了有限的三次样条模型来估计它们的暴露-响应关系。结果表明，住宅绿色与肺炎事件的风险呈负相关。NDVI500-m缓冲液的四分位数（IQR）增加与4％相关[HR（95％CI）=0.96（0.94，0.97），P<0.001]降低肺炎事件的风险。与最低绿度四分位数(Q1)相比，最高四分位数（Q4）的肺炎发生率较低，HR（95%CI）估计为0.91（0.87，0.95）（P值<0.001）。基于NDVI1000-m缓冲液的分析获得了类似的结果。此外，发现按年龄和收入进行的修改对住宅绿色度和突发肺炎之间的联系产生了显着影响。这些发现提出了潜在的有效预防突发肺炎的方法，为促进住宅绿色化建设提供了科学依据。
