关键词: muscle‐invasive bladder cancer negative surgical margins partial cystectomy squamous cell carcinoma

来  源:   DOI:10.1002/ccr3.9019   PDF(Pubmed)

Abstract:
UNASSIGNED: The \"gold standard\" treatment for Squamous cell carcinoma (SCC) is radical cystectomy and different management approaches that combine chemotherapy and radiation in a neoadjuvant or adjuvant setting have been attempted with varying degrees of effectiveness. For certain individuals, partial cystectomy offers sufficient local control for muscle-invasive bladder cancer. Lifelong follow-up with cystoscopy is advised due to the possibility of potentially fatal late recurrence.
UNASSIGNED: Squamous cell carcinoma (SCC) of the bladder is a rare urologic malignancy that is estimated to affect 3%-5% of the bladder cases. SCC of the bladder remains the most common subtype throughout Africa. Most of the literatures focused on the management of Urothelial carcinoma (UC), with fewer discussions on SCC management. UC typically presents with painless hematuria, whereas SCC presents with painful hematuria, bladder mass, and necroturia. SCC is mostly radioresistant and does not respond to chemotherapy. The mainstay treatment is partial cystectomy or radical cystectomy, which can be performed through open surgery or laparoscopic or robot-assisted approaches, all of which have acceptable results. We report a patient with a favorable outcome following partial cystectomy who was managed by open surgery. At the 12-month follow-up, the patient remained asymptomatic with good surgical outcomes.
摘要:
鳞状细胞癌(SCC)的“金标准”治疗是根治性膀胱切除术,并且尝试了在新辅助或辅助环境中结合化疗和放疗的不同管理方法,效果不同。对某些人来说,膀胱部分切除术为肌层浸润性膀胱癌提供了足够的局部控制。由于可能致命的晚期复发,建议进行膀胱镜检查的终身随访。
膀胱鳞状细胞癌(SCC)是一种罕见的泌尿系恶性肿瘤,估计会影响3%-5%的膀胱病例。膀胱SCC仍然是整个非洲最常见的亚型。大多数文献集中在尿路上皮癌(UC)的治疗,关于SCC管理的讨论较少。UC通常表现为无痛性血尿,而SCC表现为疼痛性血尿,膀胱肿块,和死尿症.SCC主要是耐放射性的,对化疗没有反应。主要治疗方法是膀胱部分切除术或根治性膀胱切除术,可以通过开放手术或腹腔镜或机器人辅助方法进行,所有这些都有可以接受的结果。我们报告了一名膀胱部分切除术后结果良好的患者,该患者通过开放手术进行了治疗。在12个月的随访中,患者仍无症状,手术效果良好.
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