PDF(Pubmed)
Abstract：
UNASSIGNED: Catatonia is a syndrome characterized by psychomotor and behavioral disturbances and is associated with a substantially increased mortality risk in adolescent patients. There is a dearth of published literature describing treatment strategies for pediatric patients with catatonia. This dual-case series will describe the treatment course of 2 adolescent patients with catatonia at our pediatric inpatient psychiatric facility.
UNASSIGNED: This case series presents 2 adolescent patients (a 17-year-old male and a 16-year-old female) who initially presented with worsening agitation and paranoia, later developing catatonia. Both patients required long durations of hospitalization and were treated with high-dose lorazepam before requiring the addition of electroconvulsive therapy (ECT).
UNASSIGNED: Treatment of pediatric patients with catatonia creates a significant burden on patients, families, and the healthcare system. Treatment with high-dose benzodiazepines is high risk, while ECT is both difficult to access and comes with its own risks. Both patients discussed are transitional age, meaning they will soon be young adults who will continue to require high-level psychiatric care. Psychiatric pharmacists have a large role to play in ensuring safe medication management for these complex patients.
UNASSIGNED: This case series of 2 adolescent patients with catatonia demonstrates marginal reduction in symptoms with high-dose lorazepam in conjunction with ECT, with minimal side effects. This case series adds to the limited available literature regarding treatment of catatonia in pediatric patients and highlights the need for further study into effective treatment alternatives.
UNASSIGNED: This case series presents 2 adolescent patients (a 17-year-old male and a 16-year-old female) who initially presented with worsening agitation and paranoia, later developing catatonia. Both patients required long durations of hospitalization and were treated with high-dose lorazepam before requiring the addition of electroconvulsive therapy (ECT).
UNASSIGNED: Treatment of pediatric patients with catatonia creates a significant burden on patients, families, and the healthcare system. Treatment with high-dose benzodiazepines is high risk, while ECT is both difficult to access and comes with its own risks. Both patients discussed are transitional age, meaning they will soon be young adults who will continue to require high-level psychiatric care. Psychiatric pharmacists have a large role to play in ensuring safe medication management for these complex patients.
UNASSIGNED: This case series of 2 adolescent patients with catatonia demonstrates marginal reduction in symptoms with high-dose lorazepam in conjunction with ECT, with minimal side effects. This case series adds to the limited available literature regarding treatment of catatonia in pediatric patients and highlights the need for further study into effective treatment alternatives.
摘要：
■紧张症是一种以精神运动和行为障碍为特征的综合征，与青少年患者的死亡风险大幅增加有关。缺乏已发表的文献来描述小儿紧张症患者的治疗策略。这个双病例系列将描述在我们的儿科住院精神病院中2名患有紧张症的青少年患者的治疗过程。
本系列病例介绍了2名青少年患者（一名17岁男性和一名16岁女性），他们最初表现为躁动和妄想症恶化，后来发展为紧张症。两名患者均需要长期住院，并在需要加电惊厥治疗（ECT）之前接受了大剂量劳拉西泮治疗。
■小儿紧张症患者的治疗给患者带来了巨大的负担，家庭,和医疗保健系统。用大剂量苯二氮卓类药物治疗是高风险的，而ECT既难以获得，又有自身的风险。讨论的两个病人都是过渡年龄，这意味着他们很快就会成为年轻人，他们将继续需要高水平的精神病治疗。精神科药剂师在确保这些复杂患者的安全药物管理方面发挥着重要作用。
■本病例系列2名患有紧张症的青少年患者在接受高剂量劳拉西泮联合ECT治疗时症状有轻微减轻，副作用最小。该病例系列增加了有关儿科患者卡顿多症治疗的有限文献，并强调需要进一步研究有效的治疗方法。
本系列病例介绍了2名青少年患者（一名17岁男性和一名16岁女性），他们最初表现为躁动和妄想症恶化，后来发展为紧张症。两名患者均需要长期住院，并在需要加电惊厥治疗（ECT）之前接受了大剂量劳拉西泮治疗。
■小儿紧张症患者的治疗给患者带来了巨大的负担，家庭,和医疗保健系统。用大剂量苯二氮卓类药物治疗是高风险的，而ECT既难以获得，又有自身的风险。讨论的两个病人都是过渡年龄，这意味着他们很快就会成为年轻人，他们将继续需要高水平的精神病治疗。精神科药剂师在确保这些复杂患者的安全药物管理方面发挥着重要作用。
■本病例系列2名患有紧张症的青少年患者在接受高剂量劳拉西泮联合ECT治疗时症状有轻微减轻，副作用最小。该病例系列增加了有关儿科患者卡顿多症治疗的有限文献，并强调需要进一步研究有效的治疗方法。
