Abstract：
BACKGROUND: Anterolateral tibial bowing associated with congenital tibial pseudarthrosis occurs often in patients with neurofibromatosis type 1 and results from the inability of the fractured bone to unite, leading to persistent nonunion, abnormal bone growth, and further bowing of the tibia. Current surgical and nonsurgical approaches demonstrate persistent nonunion or refracture, often resulting in amputation.
METHODS: This report describes the management of 3 patients with anterolateral tibial bowing and NF1 who underwent distal tibia-guided growth.
RESULTS: The patients had an average age of 1.6 years at initial operation, with a total of 3 to 4 surgeries over an average of 2.1 years. The latest follow-up on all patients is included, at a mean of 5.1 years after the initial operation. All 3 patients experienced substantial functional improvement and improved alignment of the mechanical axis of the tibia. One patient has experienced refracture.
CONCLUSIONS: Our study indicates that guided growth can serve as an additional surgical option to improve ALTB and potentially reduce the risk of fracture and pseudarthrosis by restoring normal mechanical alignment.
METHODS: Level-IV, Case Series.
METHODS: This report describes the management of 3 patients with anterolateral tibial bowing and NF1 who underwent distal tibia-guided growth.
RESULTS: The patients had an average age of 1.6 years at initial operation, with a total of 3 to 4 surgeries over an average of 2.1 years. The latest follow-up on all patients is included, at a mean of 5.1 years after the initial operation. All 3 patients experienced substantial functional improvement and improved alignment of the mechanical axis of the tibia. One patient has experienced refracture.
CONCLUSIONS: Our study indicates that guided growth can serve as an additional surgical option to improve ALTB and potentially reduce the risk of fracture and pseudarthrosis by restoring normal mechanical alignment.
METHODS: Level-IV, Case Series.
摘要：
背景：与先天性胫骨假关节相关的胫骨前外侧弯曲通常发生在1型神经纤维瘤病患者中，并且由于骨折的骨无法结合，导致持续的不愈合，骨生长异常,进一步弯曲胫骨。目前的手术和非手术入路表现为持续性骨不连或再骨折，经常导致截肢。
方法：本报告描述了3例胫骨前外侧弯曲和NF1患者在胫骨远端引导下生长的治疗。
结果：患者在初次手术时的平均年龄为1.6岁，平均2.1年共进行3至4次手术。包括对所有患者的最新随访，在初次手术后平均5.1年。所有3名患者均经历了实质性的功能改善，并改善了胫骨机械轴的对准。一名患者经历了再骨折。
结论：我们的研究表明，引导生长可以作为一种额外的手术选择来改善ALTB，并可能通过恢复正常的机械对准来降低骨折和假关节的风险。
方法：四级，案例系列。
方法：本报告描述了3例胫骨前外侧弯曲和NF1患者在胫骨远端引导下生长的治疗。
结果：患者在初次手术时的平均年龄为1.6岁，平均2.1年共进行3至4次手术。包括对所有患者的最新随访，在初次手术后平均5.1年。所有3名患者均经历了实质性的功能改善，并改善了胫骨机械轴的对准。一名患者经历了再骨折。
结论：我们的研究表明，引导生长可以作为一种额外的手术选择来改善ALTB，并可能通过恢复正常的机械对准来降低骨折和假关节的风险。
方法：四级，案例系列。
