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Abstract：
The use of fibrin glue for inguinal hernia mesh fixation has been suggested to be effective in preventing hematomas and reducing postoperative pain compared to tacks and sutures.. The effect of fibrin glue can vary significantly based on the device used. This study assessed the efficacy of fibrin glue based on the type of devices used in an ex vivo system. The rabbit\'s abdominal wall was trimmed to a size of 3.0 × 6.0 cm and was secured at the edges with metal fixtures. To measure the maximum tensile strength at the point of adhesion failure, the hernia mesh was fixed to the rabbit\'s abdominal wall using fibrin glue in a 2 cm square area, left for 3 min, and then pulled at a speed of 50 cm/min. The test was conducted 10 times for each group. The median (minimum-maximum) tensile strength values using the spraying, two-liquid mixing, and sequential layering methods were 3.58 (1.99-4.95), 0.51 (0.27-1.89), and 1.32 (0.63-1.66) N, respectively. The spraying method had predominantly higher tensile strength values than the two-liquid mixing and sequential layering methods (P < 0.01). In conclusion, in hernia mesh fixation, the spraying method can be adopted to achieve appropriate adhesive effects.
摘要：
与平头钉和缝线相比，使用纤维蛋白胶进行腹股沟疝网片固定术已被认为可有效预防血肿并减轻术后疼痛。.纤维蛋白胶的作用可基于所使用的装置而显著变化。这项研究根据离体系统中使用的设备类型评估了纤维蛋白胶的功效。将兔子的腹壁修剪成3.0×6.0cm的尺寸,并用金属固定装置固定在边缘处。要测量粘合破坏点处的最大拉伸强度，用纤维蛋白胶将疝网片固定在2厘米见方的兔腹壁上，离开3分钟,然后以50cm/min的速度拉动。每组进行10次测试。使用喷涂的中值（最小-最大）抗拉强度值，双液混合,顺序分层方法为3.58(1.99-4.95)，0.51（0.27-1.89），和1.32(0.63-1.66)N，分别。与双液混合和顺序分层方法相比，喷涂方法具有更高的拉伸强度值（P<0.01）。总之,在疝网片固定术中，可以采用喷涂方法来达到适当的粘合效果。
