UNASSIGNED: Systematic search was carried out in the electronic data-bases i.e. PubMed, Cochrane and Google scholar for original studies related to TB in OSCC. The assessment of risk bias was done using QUIPS tool. Meta-analysis was done using STATA software.
UNASSIGNED: A total of 25 articles were included. A significant association was noted for overall survival and prognosis but not for TB LNM in OSCC. Meta-analysis revealed a pooled estimate i.e odds ratio of 2.10 (CI - 0.00 - 4.20) for TB and LNM while for overall survival, it was 2.29 (CI-1.81-2.76).
UNASSIGNED: Tumor budding though is strongly associated with LNM in OSCC did not show significant relationship in this systematic review but demonstrated a higher correlation with overall survival. It highlights that TB is an important parameter for prognosis of oral cancer but its potential in prediction of LNM needs further validation.
■在电子数据库中进行了系统搜索,即PubMed,Cochrane和Google学者在OSCC中与结核病相关的原始研究。使用QUIPS工具进行风险偏倚评估。采用STATA软件进行Meta分析。
■共包括25篇文章。OSCC中的TBLNM与总体生存率和预后之间存在显着关联,但与TBLNM无关。荟萃分析显示,结核病和LNM的比值比为2.10(CI-0.00-4.20),而总生存率为,它是2.29(CI-1.81-2.76)。
■虽然肿瘤出芽与OSCC中的LNM密切相关,但在本系统评价中没有显示出显著的相关性,但与总生存期有更高的相关性。它强调了TB是口腔癌预后的重要参数,但其预测LNM的潜力需要进一步验证。