PDF(Pubmed)
Abstract：
UNASSIGNED: Magnetic resonance imaging (MRI) is a routinely used imaging modality for pre-treatment radiologic evaluation of tongue carcinoma, providing accurate information regarding the extent of the disease.
UNASSIGNED: To investigate the role of MRI-derived depth of invasion and tumor thickness evaluation in squamous cell carcinoma of the tongue, and to assess if any correlation exists between depth of invasion, tumor thickness, nodal metastasis, muscles, and space involved.
UNASSIGNED: Thirty-three patients with oral squamous cell carcinoma of the tongue who had undergone pre-treatment MRI and excisional biopsy were included. The tumor thickness (TT) and depth of invasion (DOI) were evaluated on MRI and histopathologic images.
UNASSIGNED: The relation between different methodologies for assessing showed a very high correlation for the tumor tissue thickness (r = 0.99, p < 0.05) and depth of invasion (r = 0.82, p < 0.05). The tumor thickness and the depth of invasion increased with the loss of differentiation in the carcinoma histopathologically. As the depth of invasion increases, the extent of the spread of the carcinoma to tongue musculature, lingual septum, and spaces also increases.
UNASSIGNED: The present study has depicted a high correlation between the tumor thickness and the depth of invasion between MRI and histopathological findings and is the first of its kind to correlate DOI to the invasiveness of the disease.
UNASSIGNED: To investigate the role of MRI-derived depth of invasion and tumor thickness evaluation in squamous cell carcinoma of the tongue, and to assess if any correlation exists between depth of invasion, tumor thickness, nodal metastasis, muscles, and space involved.
UNASSIGNED: Thirty-three patients with oral squamous cell carcinoma of the tongue who had undergone pre-treatment MRI and excisional biopsy were included. The tumor thickness (TT) and depth of invasion (DOI) were evaluated on MRI and histopathologic images.
UNASSIGNED: The relation between different methodologies for assessing showed a very high correlation for the tumor tissue thickness (r = 0.99, p < 0.05) and depth of invasion (r = 0.82, p < 0.05). The tumor thickness and the depth of invasion increased with the loss of differentiation in the carcinoma histopathologically. As the depth of invasion increases, the extent of the spread of the carcinoma to tongue musculature, lingual septum, and spaces also increases.
UNASSIGNED: The present study has depicted a high correlation between the tumor thickness and the depth of invasion between MRI and histopathological findings and is the first of its kind to correlate DOI to the invasiveness of the disease.
摘要：
■磁共振成像（MRI）是一种常规使用的成像方式，用于舌癌的治疗前放射学评估，提供有关疾病程度的准确信息。
■探讨MRI浸润深度和肿瘤厚度评估在舌鳞状细胞癌中的作用，并评估入侵深度之间是否存在任何相关性，肿瘤厚度,淋巴结转移,肌肉,涉及空间。
■33例口腔舌鳞状细胞癌患者接受了治疗前MRI和切除活检。在MRI和组织病理学图像上评估肿瘤厚度（TT）和浸润深度（DOI）。
■不同评估方法之间的关系表明，肿瘤组织厚度（r=0.99，p<0.05）和浸润深度（r=0.82，p<0.05）具有非常高的相关性。在组织病理学上，肿瘤的厚度和浸润深度随着分化的丧失而增加。随着入侵深度的增加，癌症扩散到舌头肌肉的程度，舌隔，空间也增加了。
■本研究描述了MRI和组织病理学发现之间的肿瘤厚度和浸润深度之间的高度相关性，并且是将DOI与疾病的侵袭性相关联的首例。
■探讨MRI浸润深度和肿瘤厚度评估在舌鳞状细胞癌中的作用，并评估入侵深度之间是否存在任何相关性，肿瘤厚度,淋巴结转移,肌肉,涉及空间。
■33例口腔舌鳞状细胞癌患者接受了治疗前MRI和切除活检。在MRI和组织病理学图像上评估肿瘤厚度（TT）和浸润深度（DOI）。
■不同评估方法之间的关系表明，肿瘤组织厚度（r=0.99，p<0.05）和浸润深度（r=0.82，p<0.05）具有非常高的相关性。在组织病理学上，肿瘤的厚度和浸润深度随着分化的丧失而增加。随着入侵深度的增加，癌症扩散到舌头肌肉的程度，舌隔，空间也增加了。
■本研究描述了MRI和组织病理学发现之间的肿瘤厚度和浸润深度之间的高度相关性，并且是将DOI与疾病的侵袭性相关联的首例。
