PDF(Pubmed)
Abstract：
This article presents a case report of a 45-year-old male with neurofibromatosis type I (NF1) who developed a high-grade malignant peripheral nerve sheath tumor (MPNST) originating from a neurofibroma within the common peroneal nerve over popliteal fossa. MPNSTs are aggressive tumors associated with NF1, causing significant mortality. The patient underwent tumor resection surgery and received postoperative radiation therapy. Follow-up examinations showed no impairment of motor function and no tumor recurrence after regular MRI evaluation for four years. This article explores the challenges of distinguishing benign neurofibromas from malignant MPNST via MRI image and biopsy, and achieving a balance between tumor excision and preserving nerve functionality during surgical treatment. However, caution is warranted due to the risk of recurrence.
摘要：
本文介绍了一例45岁男性I型神经纤维瘤病（NF1）的病例报告，该病例发展为高级别恶性周围神经鞘瘤（MPNST），起源于the窝上腓总神经内的神经纤维瘤。MPNSTs是与NF1相关的侵袭性肿瘤,导致显著的死亡率。患者接受了肿瘤切除手术，并接受了术后放射治疗。经过4年的常规MRI评估，随访检查显示运动功能无损害，肿瘤无复发。本文探讨了通过MRI图像和活检区分良性神经纤维瘤和恶性MPNST的挑战。并在手术治疗期间实现肿瘤切除和保留神经功能之间的平衡。然而,由于复发的风险，谨慎是必要的。
