Abstract：
OBJECTIVE: Limited data exist on the effectiveness of oral health preventive programs in children with Neurodevelopmental Disorders (NDD). The aim of this study was to evaluate the effectiveness of an individualized preventive oral health program for preschool children with NDD at a rehabilitation center, over a two years period.
RESULTS: In this study, 102 preschool children with NDD were assessed for caries (dmft), oral hygiene status (Green & Vermillion Index) and presence of developmental dental defects. An individualized preventive program was applied based on caries risk and children were followed for two years. Effectiveness of the program was assessed for caries and dental plaque change and explanatory individual factors were used in multivariate models. After two years prospective, dmft increased significantly from 1.1 (SD = 2.7) to 2.04 (SD = 3.6), while GVPI was reduced significantly from 1.8 (SD = 0.9) to 1.4 (SD = 0.9). Children in the moderate and high-risk groups missed significantly more follow-ups compared to the low caries risk group (p < .001) while older maternal age (OR = 1.38, 95%CI = 1.057-1.808) and consumption of more than three sugary snacks/day (OR = 0.005, 95%CI = 0-0.0794) were significantly correlated with dental caries.
CONCLUSIONS: The individualized preventive program for preschool children with NDD was effective in improving oral hygiene but not dental caries status.
RESULTS: In this study, 102 preschool children with NDD were assessed for caries (dmft), oral hygiene status (Green & Vermillion Index) and presence of developmental dental defects. An individualized preventive program was applied based on caries risk and children were followed for two years. Effectiveness of the program was assessed for caries and dental plaque change and explanatory individual factors were used in multivariate models. After two years prospective, dmft increased significantly from 1.1 (SD = 2.7) to 2.04 (SD = 3.6), while GVPI was reduced significantly from 1.8 (SD = 0.9) to 1.4 (SD = 0.9). Children in the moderate and high-risk groups missed significantly more follow-ups compared to the low caries risk group (p < .001) while older maternal age (OR = 1.38, 95%CI = 1.057-1.808) and consumption of more than three sugary snacks/day (OR = 0.005, 95%CI = 0-0.0794) were significantly correlated with dental caries.
CONCLUSIONS: The individualized preventive program for preschool children with NDD was effective in improving oral hygiene but not dental caries status.
摘要：
目的：关于神经发育障碍（NDD）儿童口腔健康预防计划有效性的数据有限。这项研究的目的是评估在康复中心针对NDD学龄前儿童的个性化预防性口腔健康计划的有效性，超过两年。
结果：在这项研究中，对102名患有NDD的学龄前儿童进行了龋齿评估（dmft），口腔卫生状况(绿色和朱红色指数)和发育性牙齿缺陷的存在。根据龋齿风险应用了个性化的预防计划，并对儿童进行了两年的随访。评估龋齿和牙菌斑变化的程序的有效性，并在多变量模型中使用解释性的个体因素。经过两年的前瞻性，dmft从1.1(SD=2.7)显著增加到2.04(SD=3.6)，而GVPI从1.8(SD=0.9)显著降低至1.4(SD=0.9)。与低龋风险组相比，中高风险组的儿童错过了更多的随访（p<.001），而年龄较大的母亲（OR=1.38，95CI=1.057-1.808）和每天食用超过3份含糖零食（OR=0.005，95CI=0-0.0794）与龋齿显着相关。
结论：针对NDD学龄前儿童的个性化预防计划可有效改善口腔卫生，但不能改善龋齿状况。
结果：在这项研究中，对102名患有NDD的学龄前儿童进行了龋齿评估（dmft），口腔卫生状况(绿色和朱红色指数)和发育性牙齿缺陷的存在。根据龋齿风险应用了个性化的预防计划，并对儿童进行了两年的随访。评估龋齿和牙菌斑变化的程序的有效性，并在多变量模型中使用解释性的个体因素。经过两年的前瞻性，dmft从1.1(SD=2.7)显著增加到2.04(SD=3.6)，而GVPI从1.8(SD=0.9)显著降低至1.4(SD=0.9)。与低龋风险组相比，中高风险组的儿童错过了更多的随访（p<.001），而年龄较大的母亲（OR=1.38，95CI=1.057-1.808）和每天食用超过3份含糖零食（OR=0.005，95CI=0-0.0794）与龋齿显着相关。
结论：针对NDD学龄前儿童的个性化预防计划可有效改善口腔卫生，但不能改善龋齿状况。
