Mesh : Humans Female Male Anxiety / diagnostic imaging psychology Attention / physiology Diffusion Tensor Imaging Adolescent Young Adult Child Abuse / psychology White Matter / diagnostic imaging pathology

来  源:   DOI:10.1097/WNR.0000000000002053

Abstract:
This study explores the neural correlates between attentional control and trait anxiety among youth with a history of childhood maltreatment. Using diffusion tensor imaging, we investigated the microstructural integrity of brain white matter, particularly focusing on the right superior corona radiata (SCA-R). A total of 173 university students with experiences of childhood maltreatment underwent behavioral assessments using the Attentional Control Scale and trait anxiety measurements via the Spielberger State-Trait Anxiety Inventory. Our analysis found significant correlations between fractional anisotropy values in the SCA-R and trait anxiety levels, controlled for age and sex. Notably, SCA-R fractional anisotropy values partially mediated the relationship between attentional control and trait anxiety, suggesting a potential pathway through which attentional control could mitigate trait anxiety. These insights highlight attentional control as a potential mitigating factor against trait anxiety, particularly noting the partial mediation role of the SCA-R. Importantly, this study is descriptive and correlative, highlighting associations rather than causal relationships among the variables studied. These findings enhance our understanding of the neural mechanisms underlying anxiety in individuals with a history of childhood maltreatment.
摘要:
这项研究探讨了有童年虐待史的年轻人的注意力控制与特质焦虑之间的神经相关性。使用扩散张量成像,我们研究了脑白质的微结构完整性,特别关注右上电晕辐射(SCA-R)。共有173名有儿童虐待经历的大学生使用注意控制量表进行了行为评估,并通过Spielberger状态特质焦虑量表进行了特质焦虑测量。我们的分析发现SCA-R中的分数各向异性值与特质焦虑水平之间存在显着相关性,控制年龄和性别。值得注意的是,SCA-R分数各向异性值部分介导了注意控制与特质焦虑之间的关系,提示注意控制可以减轻特质焦虑的潜在途径。这些见解强调了注意力控制是对抗特质焦虑的潜在缓解因素,特别注意SCA-R的部分调解作用重要的是,这项研究是描述性和相关性的,突出所研究变量之间的关联而不是因果关系。这些发现增强了我们对有童年虐待史的个体焦虑的神经机制的理解。
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