Abstract：
Fine-needle aspiration (FNA) is a safe, cost-effective diagnostic procedure used in the evaluation of thyroid nodules. The number of thyroid FNAs has dramatically increased over the past few years. In the absence of standardized procedures regarding the number of needle passes needed for diagnosis and the lack of clarity on the use of conventional smears (CS) versus liquid-based preparations (LBP), the demand of thyroid FNAs has led to increased workload on cytology laboratories, which can negatively affect patient safety. We implemented a standardized two needle passes for CS and collection of all needle rinses and additional pass material in CytoRich Red for ThinPrep LBP and compared the non-diagnostic and diagnostic rates before and after this intervention. There were 290 pre-intervention cases and 348 post-intervention cases; of which, there were 17 (5.9%) non-diagnostic cases of the pre-intervention group and 27 (7.8) non-diagnostic cases of the post-intervention group. There was no statistically significant difference in non-diagnostic and diagnostic rates before and after the change (p = 0.347 by two-tailed Z test).
摘要：
细针抽吸术（FNA）是一种安全的，用于评估甲状腺结节的具有成本效益的诊断程序。在过去几年中，甲状腺FNA的数量急剧增加。在缺乏有关诊断所需的针头通过次数的标准化程序以及使用常规涂片（CS）与液基制剂（LBP）的清晰度不足的情况下，甲状腺FNA的需求导致细胞学实验室的工作量增加，这会对患者安全产生负面影响。我们为CS实施了标准化的两针通过，并在ThinPrepLBP的CytoRichRed中收集了所有针头冲洗液和其他通过材料，并比较了此干预前后的非诊断和诊断率。干预前病例290例，干预后病例348例；其中，干预前组有17例(5.9%)非诊断病例,干预后组有27例(7.8%)非诊断病例.改变前后的非诊断率和诊断率无统计学差异(双尾Z检验p=0.347)。
