UNASSIGNED: A triple-blind, randomised, controlled clinical trial was conducted on 117 lactating mothers who had given birth to healthy infants aged 10-15 days and who received cumin oral drops (n = 39), nettle oral drops (n = 39) or placebo (n = 39) from August 2020 to March 2021. The participants were recruited from a regional public health care centre affiliated with Iran University of Medical Sciences of Tehran, Tehran, Iran. The 3 study groups received 15 drops thrice a day for 4 weeks. Infant weight, breastfeeding frequency, number of wet diapers, diaper weight and frequency of infant defecation were evaluated before and after the intervention.
UNASSIGNED: At the beginning of the trial, no statistically significant differences were observed between the 3 groups for infant weight (P = 0.891), breastfeeding frequency (P = 0.921), number of wet diapers (P = 0.783), diaper weight (P = 0.841) and frequency of infant defecation (P = 0.898). However, following the intervention, the mean scores of all indicators were significantly higher in the experimental groups than in the placebo group (P <0.001). In addition, all the indicators in the cumin group increased significantly compared to those in the nettle group (P <0.001).
UNASSIGNED: Considering the effectiveness of cumin and nettle drops in increasing milk and the availability of these native plants in Iran, it is suggested that they, especially cumin, be used postpartum to increase breast milk production.
■三盲,随机化,对117名哺乳期母亲进行了对照临床试验,这些母亲生育了10-15天的健康婴儿,并接受了孜然口服滴剂(n=39),从2020年8月至2021年3月,荨麻口服滴剂(n=39)或安慰剂(n=39)。参与者是从德黑兰伊朗医科大学附属的地区公共卫生保健中心招募的,德黑兰,伊朗。3个研究组每天三次接受15滴,持续4周。婴儿体重,母乳喂养频率,湿尿布的数量,在干预前后评估尿布重量和婴儿排便频率。
■在审判开始时,3组婴儿体重差异无统计学意义(P=0.891),母乳喂养频率(P=0.921),湿尿布数量(P=0.783),尿布重量(P=0.841)和婴儿排便频率(P=0.898)。然而,干预之后,实验组各项指标的平均得分均显著高于安慰剂组(P<0.001).此外,孜然组各项指标均显著高于荨麻组(P<0.001)。
■考虑到孜然和荨麻滴在增加牛奶中的有效性以及伊朗这些本地植物的可用性,有人建议他们,尤其是小茴香,产后用于增加母乳产量。