PDF(Pubmed)
Abstract：
The zoonotic hookworm species Ancylostoma ceylanicum has drawn more attention recently because of its potential impact on public health. Although A. duodenale and Necator americanus are more common, A. ceylanicum is still known to play a major role in human infections, particularly in regions where close human-animal interactions are prevalent. While there has been a notable increase in documenting the presence of A. ceylanicum in the Asia-Pacific area, bottlenecks remains in understanding its epidemiology in Bangladesh. This report highlights the first documented case of Ancylostoma ceylanicum infection isolated and identified in a 15-year-old girl experiencing frequent diarrhea and weakness, residing in an urban tea garden area in Sylhet, Bangladesh. Microscopic examination of stool samples revealed the presence of hookworm eggs and subsequent culture led to the observation of larvae. Molecular investigation by amplifying Internal Transcribed Spacer (ITS1+) regions of the ribosomal deoxyribonucleic acid (rDNA) confirmed the infection as A. ceylanicum. The identification of Ancylostoma ceylanicum in a human host in Bangladesh carries significant implications for global health. The careful measurement of eggs and larvae, coupled with molecular analysis, serves as an appropriate diagnostic strategy for confirming the infections. This finding emphasizes the emergence of A. ceylanicum as a zoonotic infection in endemic regions and calls for increased awareness among healthcare professionals and the general public.
摘要：
由于人畜共患钩虫对公共卫生的潜在影响，最近引起了更多关注。尽管十二指肠A和美洲Necator更为常见，众所周知，头孢霉素在人类感染中起着重要作用，特别是在人与动物密切互动的地区。虽然记录在亚太地区存在塞利兰酵母的情况显着增加，在了解孟加拉国的流行病学方面仍然存在瓶颈。本报告重点介绍了在一名15岁女孩中发现并发现的第一例有记录的头孢囊虫感染病例，该女孩患有频繁的腹泻和虚弱，居住在Sylhet的城市茶园地区，孟加拉国。粪便样品的显微镜检查显示存在钩虫卵，随后的培养导致观察到幼虫。通过扩增核糖体脱氧核糖核酸（rDNA）的内部转录间隔区（ITS1）进行的分子研究证实了感染为头孢曲霉。在孟加拉国的人类宿主中鉴定cycylostomaceylanicum对全球健康具有重要意义。仔细测量卵和幼虫，加上分子分析，作为确认感染的适当诊断策略。这一发现强调了头孢霉素在流行地区作为人畜共患感染的出现，并呼吁提高医疗保健专业人员和公众的认识。
