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Abstract：
Background The associations and risk factors for venous thromboembolism (VTE) among hospitalized COVID-19 patients remain ambiguous in the literature, with some conflicting findings, especially in Saudi Arabia. In this study, we aim to elaborate on these data by examining regional patient populations and exploring the incidence, lab findings, and outcomes of VTE among hospitalized COVID-19 patients known to have diabetes mellitus (DM). Methodology This cross-sectional study was conducted at King Abdulaziz Medical City in Riyadh. The BestCare system was used to collect patients\' data between September 2020 and February 2022. JMP15 was used for data analysis. Frequencies and percentages were used for categorical data, and median and interquartile ranges were used for quantitative data. The chi-square and Kruskal-Wallis rank-sum tests were used to assess the difference between categorical and quantitative variables, respectively. Nominal logistical regression was used to assess diabetes as a risk factor for developing VTE among COVID-19 patients. Results Data from 153 admitted patients were collected after they satisfied the inclusion criteria. Of these patients, 39 (25.49%) developed VTE. The demographic data included age group, gender, and DM status presented as frequencies and percentages. Through bivariate analysis, patients with longer hospital stays had at least one episode of VTE (p = 0.0072). Using nominal logistic regression analysis, diabetes as a risk factor (odds ratio = 4.11, confidence interval = 0.955-5.05, p = 0.0287) was significantly associated with the development of VTE in COVID-19 patients. Conclusions Based on our study, diabetes proved significant when evaluating the possible factors regarding VTE development in COVID-19 patients. In addition, the length of stay also played a critical role in the severity of VTE in COVID-19 patients. Similar studies should be conducted on a national scale in Saudi Arabia to accomplish two goals: first, to gain further understanding of the impact of the variables investigated in our population, and second, to publish data that are more generalizable to the larger population of Saudi Arabia.
摘要：
背景：住院COVID-19患者静脉血栓栓塞症（VTE）的相关性和危险因素在文献中仍然不明确，有一些相互矛盾的发现，尤其是在沙特阿拉伯。在这项研究中,我们的目标是通过检查区域患者人群和探索发病率来详细说明这些数据，实验室发现,已知患有糖尿病（DM）的住院COVID-19患者的VTE结局。方法这项横断面研究是在利雅得的阿卜杜勒阿齐兹国王医疗城进行的。BestCare系统用于收集2020年9月至2022年2月之间的患者数据。使用JMP15进行数据分析。频率和百分比用于分类数据，以及中位数和四分位数范围用于定量数据。卡方和Kruskal-Wallis秩和检验用于评估分类变量和定量变量之间的差异，分别。在COVID-19患者中，使用名义后勤回归评估糖尿病是发生VTE的危险因素。结果153例患者均符合纳入标准,收集数据。在这些病人中,39例(25.49%)发展了VTE。人口统计数据包括年龄组，性别,和DM状态以频率和百分比表示。通过双变量分析，住院时间较长的患者至少有1次VTE发作(p=0.0072).使用名义逻辑回归分析，在COVID-19患者中,糖尿病作为危险因素(比值比=4.11,置信区间=0.955~5.05,p=0.0287)与VTE的发生显著相关.结论根据我们的研究，在评估COVID-19患者VTE发展的可能因素时，糖尿病被证明是有意义的。此外,住院时间对COVID-19患者VTE的严重程度也起关键作用.沙特阿拉伯应该在全国范围内进行类似的研究，以实现两个目标：第一，为了进一步了解我们人口中调查的变量的影响，第二,发布更可推广到沙特阿拉伯更多人口的数据。
