关键词: Indocyanine green fluorescence imaging angiosome chronic limb-threatening ischemia foot perfusion revascularization

Mesh : Humans Prospective Studies Aged Male Female Foot / blood supply surgery Middle Aged Endovascular Procedures / methods Regional Blood Flow Diabetic Foot / surgery Peripheral Arterial Disease / surgery physiopathology diagnostic imaging Popliteal Artery / surgery diagnostic imaging Aged, 80 and over Treatment Outcome Vascular Surgical Procedures / methods

来  源:   DOI:10.1177/14574969241242205

Abstract:
UNASSIGNED: In retrospective studies, wound healing and leg salvage have been better if revascularization is targeted to the crural artery supplying arterial flow to the wound angiosome. No data exist on how revascularization changes the blood flow in foot angiosomes. The aim of this study was to evaluate the change in perfusion after infrapopliteal artery revascularization in all foot angiosomes and to compare directly revascularized (DR) angiosomes to the indirectly revascularized (IR) angiosomes.
UNASSIGNED: In this prospective study, foot perfusion was measured with indocyanine green fluorescence imaging (ICG-FI) before and after either surgical or endovascular below-knee revascularization. According to angiograms, we divided the foot angiosomes into DR and IR angiosomes. Furthermore, in a subanalysis, the IR angiosomes were graded as IR_Coll+ angiosomes if there were strong collaterals arising from the artery which was revascularized, and as IR_Coll- angiosomes if strong collaterals were not seen.
UNASSIGNED: A total of 72 feet (28 bypass, 44 endovascular revascularizations) and 282 angiosomes were analyzed. Surgical and endovascular revascularization increased perfusion significantly in both DR and IR angiosomes. After bypass surgery, the increase in DR angiosomes was 55 U and 53 U in IR angiosomes; there were no significant difference in the perfusion increase between IR and DR angiosomes. After endovascular revascularization, perfusion increased significantly more, 40 U, in DR angiosomes compared to 26 U in IR angiosomes (p < 0.05). In the subanalysis of IR angiosomes, perfusion increased significantly after surgical bypass regardless of whether strong collaterals were present or not. After endovascular revascularization, however, a significant perfusion increase was noted in the IR_Coll+ but not in the IR_Coll- subgroup.
UNASSIGNED: Open revascularization increased perfusion equally in DR and IR angiosomes, whereas endovascular revascularization increased perfusion significantly more in DR than in IR angiosomes. Strong collateral network may help increase perfusion in IR angiosomes.
摘要:
在回顾性研究中,如果将血运重建针对向伤口血管体提供动脉血流的小腿动脉,则伤口愈合和腿部抢救效果更好。没有关于血运重建如何改变足血管小体血流量的数据。这项研究的目的是评估所有足血管体的股下动脉血运重建后灌注的变化,并比较直接血运重建(DR)血管体与间接血运重建(IR)血管体。
在这项前瞻性研究中,在手术或血管内膝关节下血运重建术之前和之后,使用吲哚菁绿荧光成像(ICG-FI)测量足部灌注。根据血管造影,我们将足血管体分为DR和IR血管体。此外,在子分析中,如果血管再血管化的动脉产生了强烈的络脉,则IR血管体被分级为IR_Coll血管体,如果没有看到强烈的络脉,则作为IR_Coll-血管体。
总共72英尺(28个旁路,分析了44个血管内血运重建)和282个血管体。手术和血管内血运重建术显著增加DR和IR血管体的灌注。搭桥手术后,IR血管体DR血管体的增加分别为55U和53U;IR和DR血管体之间的灌注增加没有显著差异.血管内血运重建后,灌注明显增加,40U,与IR血管体中的26U相比(p<0.05)。在IR血管体的亚分析中,无论是否存在强大的络脉,手术旁路后灌注均显着增加。血管内血运重建后,然而,在IR_Coll+但IR_Coll-亚组没有发现显著的灌注增加。
开放血管重建术同样增加DR和IR血管体的灌注,而血管内血运重建增加DR的灌注显著高于IR血管体。强大的侧支网络可能有助于增加IR血管体的灌注。
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