Abstract:
Health surveys to assess adverse events after peripheral blood stem cell harvest (PBSCH) have conventionally been conducted by phone, but phone calls are suboptimal for conducting frequent surveys. We developed a web-based application (donor app) that enables donors to inform healthcare professionals (HCPs) of their health status as an electronic patient-reported outcome (ePRO). In this prospective observational study, we compared the usefulness of this donor app to phone calls for conducting health surveys. App users reported ePRO daily, and patients called by HCPs reported their health status at least once a week when called. The observation period was from the first administration of granulocyte colony-stimulating factor to the first follow-up visit after PBSCH, excluding the hospitalization period. Each group consisted of eight donors with a median age of 32 years (range: 19-58). Nine (56.3%) were female. There were eight related donors in the phone call group and four in the donor app group. During the observation period, HCPs obtained health status reports more frequently from app users than from phone call recipients (mean proportion of days with reports made during the observation period, 27.0% vs 53.5%; p<0.05). Average time spent by the HCPs for one follow-up and total follow-ups were both significantly shorter when the donor app was used. There were no differences in donor burden or satisfaction with donation. Our study suggests that use of a donor app could provide more detailed health survey data without increasing the burden on donors and HCPs.
摘要:
通常通过电话进行健康调查以评估外周血干细胞收获(PBSCH)后的不良事件,但是电话对于进行频繁的调查来说并不理想。我们开发了一个基于Web的应用程序(捐赠者应用程序),使捐赠者能够将其健康状况作为电子患者报告结果(ePRO)告知医疗保健专业人员(HCP)。在这项前瞻性观察研究中,我们比较了这个捐献者应用程序与电话进行健康调查的有用性。应用程序用户每天报告EPRO,HCPs呼叫的患者每周至少报告一次他们的健康状况。观察期为首次给予粒细胞集落刺激因子至PBSCH后首次随访,不包括住院期间。每组由8个供体组成,中位年龄为32岁(范围:19-58)。9名(56.3%)为女性。电话呼叫组中有8名相关捐赠者,捐赠者应用程序组中有4名相关捐赠者。在观察期间,HCP从应用程序用户那里获得健康状况报告的频率高于从电话接收者那里获得健康状况报告的频率(在观察期间报告的天数的平均比例,27.0%vs53.5%;p<0.05)。使用捐献者应用程序时,HCP进行一次随访和总随访的平均时间均明显缩短。捐赠者负担或对捐赠的满意度没有差异。我们的研究表明,使用捐赠者应用程序可以提供更详细的健康调查数据,而不会增加捐赠者和HCP的负担。