METHODS: Data from 88 patients diagnosed with FLLs by imaging who underwent EUS-FNA from 1 January 2017 to 31 August 2022 were reviewed in our retrospective study at the Second Affiliated Hospital of Soochow University and Ruijin Hospital of the School of Medicine of Shanghai Jiao Tong University. The EUS-FNA biopsy results were compared with the final diagnosis to evaluate diagnostic value. The relevant factors were analysed to determine their influence on EUS-FNA biopsy results.
RESULTS: The 88 patients analysed in this study resulted in a final diagnosis of 86 malignant and two benign cases. The overall diagnostic accuracy of EUS-FNA in FLLs was 93.18 % (82/88; 95 % Confidence Interval [CI], 87.9-98.5), with a sensitivity, specificity, positive predictive value, and negative predictive value of 93.02 % (80/86; 95 %CI, 87.6-98.4), 100 % (2/2; 95 %CI, 100-100), 100 % (80/80; 95 %CI, 100-100), and 25 % (2/8; 95 %CI, -5-55.0), respectively. The parameters related to lesion and procedure were not significantly different between these two groups (p > 0.05). The number of puncture needles in the groups showed a statistically significant difference between multiple and single punctures (p = 0.001).
CONCLUSIONS: Our data revealed that EUS-FNA is a safe and reliable diagnostic method for FLLs that shows high accuracy.
方法:我们的回顾性研究回顾了2017年1月1日至2022年8月31日在苏州大学附属第二医院和上海交通大学医学院瑞金医院接受EUS-FNA检查的88例影像学诊断为FLL患者的数据。将EUS-FNA活检结果与最终诊断结果进行比较,评价诊断价值。分析相关因素以确定其对EUS-FNA活检结果的影响。
结果:本研究分析的88例患者最终诊断为86例恶性病例和2例良性病例。EUS-FNA在FLL中的总体诊断准确性为93.18%(82/88;95%置信区间[CI],87.9-98.5),带着一种敏感性,特异性,正预测值,阴性预测值为93.02%(80/86;95CI,87.6-98.4),100%(2/2;95CI,100-100),100%(80/80;95CI,100-100),和25%(2/8;95CI,-5-55.0),分别。与病变和手术相关的参数在两组之间没有显着差异(p>0.05)。各组中穿刺针的数量在多次穿刺和单次穿刺之间显示出统计学上的显着差异(p=0.001)。
结论:我们的数据表明,EUS-FNA是一种安全可靠的FLL诊断方法,具有很高的准确性。