Abstract：
UNASSIGNED: To investigate the change in serial muscle ultrasound of rectus femoris of patients with incomplete spinal cord injury (SCI) performed within 2 months after SCI during acute rehabilitation, and the relationship with functional outcomes at 1 year post-injury.
UNASSIGNED: Prospective observational study.
UNASSIGNED: Inpatient multi-speciality tertiary rehabilitation center in Singapore.
UNASSIGNED: Fifty-four patients with incomplete SCI, defined as American Spinal Injury Association Impairment Scale B-D, with SCI above L2, were recruited from March 2020 to June 2021. Serial muscle ultrasound of the rectus femoris thickness and echo intensity were obtained at 1 week post-injury and after 2 months via standardized protocols.
UNASSIGNED: Functional Independence Measure (FIM) motor score, Lower Extremity Motor Score (LEMS), Spinal Cord Independence Measure III (SCIM III) indoor mobility component and Walking Index for Spinal Cord Injury II (WISCI II) were assessed in the first week post-admission and at 1 year.
UNASSIGNED: There was a significant positive correlation between change in rectus femoris muscle thickness over 2 months and FIM motor score (P < 0.001), LEMS (P < 0.001), SCIM III indoor mobility component (P < 0.001) and WISCI II (P < 0.001) at 1 year. For the change in echo intensity over 2 months, there was a significantly negative correlation with FIM motor score (P = 0.002), LEMS (P = 0.002), SCIM III indoor mobility component (P = 0.001) and WISCI II (P = 0.001) at 1 year.
UNASSIGNED: The findings suggest that ultrasonographic serial assessment of rectus femoris muscle thickness and echo intensity during rehabilitation may be useful for determining the long-term functional outcomes in patients with incomplete SCI.
UNASSIGNED: Prospective observational study.
UNASSIGNED: Inpatient multi-speciality tertiary rehabilitation center in Singapore.
UNASSIGNED: Fifty-four patients with incomplete SCI, defined as American Spinal Injury Association Impairment Scale B-D, with SCI above L2, were recruited from March 2020 to June 2021. Serial muscle ultrasound of the rectus femoris thickness and echo intensity were obtained at 1 week post-injury and after 2 months via standardized protocols.
UNASSIGNED: Functional Independence Measure (FIM) motor score, Lower Extremity Motor Score (LEMS), Spinal Cord Independence Measure III (SCIM III) indoor mobility component and Walking Index for Spinal Cord Injury II (WISCI II) were assessed in the first week post-admission and at 1 year.
UNASSIGNED: There was a significant positive correlation between change in rectus femoris muscle thickness over 2 months and FIM motor score (P < 0.001), LEMS (P < 0.001), SCIM III indoor mobility component (P < 0.001) and WISCI II (P < 0.001) at 1 year. For the change in echo intensity over 2 months, there was a significantly negative correlation with FIM motor score (P = 0.002), LEMS (P = 0.002), SCIM III indoor mobility component (P = 0.001) and WISCI II (P = 0.001) at 1 year.
UNASSIGNED: The findings suggest that ultrasonographic serial assessment of rectus femoris muscle thickness and echo intensity during rehabilitation may be useful for determining the long-term functional outcomes in patients with incomplete SCI.
摘要：
■探讨不完全性脊髓损伤（SCI）患者急性康复后2个月内进行的股直肌连续超声的变化，以及与损伤后1年功能结局的关系。
■前瞻性观察性研究。
■新加坡住院多专业三级康复中心。
■54名不完全SCI患者，定义为美国脊髓损伤协会损害量表B-D，SCI高于L2，于2020年3月至2021年6月招募。通过标准化方案，在受伤后1周和2个月后获得股直肌厚度和回声强度的连续肌肉超声。
■功能独立性测量（FIM）运动评分，下肢运动评分(LEMS),在入院后的第一周和1年评估了脊髓独立性措施III（SCIMIII）的室内活动成分和脊髓损伤的步行指数II（WISCIII）。
■2个月股直肌厚度变化与FIM运动评分呈显著正相关(P<0.001),LEMS（P<0.001），1年时SCIMIII室内移动性分量(P<0.001)和WISCIII(P<0.001)。对于2个月内回波强度的变化，与FIM运动评分呈显著负相关(P=0.002),LEMS（P=0.002），1年时SCIMIII室内移动性成分（P=0.001）和WISCIII（P=0.001）。
■研究结果表明，康复期间股直肌厚度和回声强度的超声连续评估可能有助于确定不完全SCI患者的长期功能结局。
■前瞻性观察性研究。
■新加坡住院多专业三级康复中心。
■54名不完全SCI患者，定义为美国脊髓损伤协会损害量表B-D，SCI高于L2，于2020年3月至2021年6月招募。通过标准化方案，在受伤后1周和2个月后获得股直肌厚度和回声强度的连续肌肉超声。
■功能独立性测量（FIM）运动评分，下肢运动评分(LEMS),在入院后的第一周和1年评估了脊髓独立性措施III（SCIMIII）的室内活动成分和脊髓损伤的步行指数II（WISCIII）。
■2个月股直肌厚度变化与FIM运动评分呈显著正相关(P<0.001),LEMS（P<0.001），1年时SCIMIII室内移动性分量(P<0.001)和WISCIII(P<0.001)。对于2个月内回波强度的变化，与FIM运动评分呈显著负相关(P=0.002),LEMS（P=0.002），1年时SCIMIII室内移动性成分（P=0.001）和WISCIII（P=0.001）。
■研究结果表明，康复期间股直肌厚度和回声强度的超声连续评估可能有助于确定不完全SCI患者的长期功能结局。
