PDF(Pubmed)
Abstract：
UNASSIGNED: Renal forniceal rupture (FR) is a unique complication of obstructive uropathy. This study aimed to identify the predictors of FR among patients presenting with renal colic due to obstructing ureteral calculi.
UNASSIGNED: After obtaining ethics approval, electronic records of patients from three National Guard hospitals in Saudi Arabia were reviewed between 2016 and 2020 to identify patients who presented with renal colic and were diagnosed with FR due to obstructive ureteric stones (FR group). An equivalent number of consecutive patients presenting with renal colic due to obstructing ureteric stones without FR was selected as a control group (non-FR group). Patients were grouped according to age group (<30, 30-40, 41-50, and >50 years), body mass index (BMI) class, gender, comorbidities, grade of hydronephrosis, location of the stone in the ureter, size of the stone (<3 mm, 3-7 mm, and >7 mm), and stone former status. Baseline patients\' and stone characteristics were compared, and a regression analysis was performed to identify predictors of FR.
UNASSIGNED: A total of 50 patients with FR were identified, and a control group of 50 patients without FR were selected. The baseline patients\' and stone demographic characteristics in terms of age (P = 0.42), gender (P = 0.275), BMI (P = 0.672), comorbidity, grade of hydronephrosis (P = 0.201), and stone location (P = 0.639) were comparable between the FR group and the non-FR group. However, the stone size was statistically significant between both groups (P = 0.014). On multivariable analysis, it was found that the stone size was associated with a significantly higher increase in the incidence of FR (odds ratio [OR]: 6.5 [1.235-34.434]; P = 0.027). Furthermore, the age group between 30 and 40 years was potentially at a lower risk for FR (OR: 0.262 [0.069-0.999]; P = 0.049).
UNASSIGNED: This multicenter study showed that the stone size 3-7 mm had a six-fold increase in the chance of FR, and the age group between 30 and 40 years is potentially at a lower risk for FR.
UNASSIGNED: After obtaining ethics approval, electronic records of patients from three National Guard hospitals in Saudi Arabia were reviewed between 2016 and 2020 to identify patients who presented with renal colic and were diagnosed with FR due to obstructive ureteric stones (FR group). An equivalent number of consecutive patients presenting with renal colic due to obstructing ureteric stones without FR was selected as a control group (non-FR group). Patients were grouped according to age group (<30, 30-40, 41-50, and >50 years), body mass index (BMI) class, gender, comorbidities, grade of hydronephrosis, location of the stone in the ureter, size of the stone (<3 mm, 3-7 mm, and >7 mm), and stone former status. Baseline patients\' and stone characteristics were compared, and a regression analysis was performed to identify predictors of FR.
UNASSIGNED: A total of 50 patients with FR were identified, and a control group of 50 patients without FR were selected. The baseline patients\' and stone demographic characteristics in terms of age (P = 0.42), gender (P = 0.275), BMI (P = 0.672), comorbidity, grade of hydronephrosis (P = 0.201), and stone location (P = 0.639) were comparable between the FR group and the non-FR group. However, the stone size was statistically significant between both groups (P = 0.014). On multivariable analysis, it was found that the stone size was associated with a significantly higher increase in the incidence of FR (odds ratio [OR]: 6.5 [1.235-34.434]; P = 0.027). Furthermore, the age group between 30 and 40 years was potentially at a lower risk for FR (OR: 0.262 [0.069-0.999]; P = 0.049).
UNASSIGNED: This multicenter study showed that the stone size 3-7 mm had a six-fold increase in the chance of FR, and the age group between 30 and 40 years is potentially at a lower risk for FR.
摘要：
■肾穹窿破裂（FR）是梗阻性尿路病变的独特并发症。这项研究旨在确定由于输尿管结石阻塞而出现肾绞痛的患者中FR的预测因素。
■获得伦理批准后，在2016年至2020年期间,我们审查了来自沙特阿拉伯3家国民警卫队医院的患者的电子记录,以确定出现肾绞痛并因梗阻性输尿管结石而被诊断为FR的患者(FR组).选择由于阻塞输尿管结石而没有FR而出现肾绞痛的连续患者作为对照组（非FR组）。患者按年龄组（<30、30-40、41-50和>50岁）分组，体重指数（BMI）等级，性别,合并症,肾积水等级,结石在输尿管中的位置，石头的大小(<3毫米，3-7毫米，且>7毫米)，和石头以前的地位。比较了基线患者和结石特征，并进行回归分析以确定FR的预测因子.
■共确定了50例FR患者，选择50例无FR患者的对照组。基线患者和结石人口统计学特征(P=0.42)，性别（P=0.275），BMI（P=0.672），合并症，肾积水分级(P=0.201),FR组和非FR组之间的结石位置（P=0.639）具有可比性。然而,两组间结石大小差异有统计学意义(P=0.014).在多变量分析中，研究发现,结石大小与FR发生率显著增加相关(比值比[OR]:6.5[1.235-34.434];P=0.027).此外，年龄在30~40岁之间的人群患FR的风险可能较低(OR:0.262[0.069~0.999];P=0.049).
■这项多中心研究表明，大小为3-7毫米的结石发生FR的机会增加了六倍，30至40岁的年龄组患FR的风险可能较低.
■获得伦理批准后，在2016年至2020年期间,我们审查了来自沙特阿拉伯3家国民警卫队医院的患者的电子记录,以确定出现肾绞痛并因梗阻性输尿管结石而被诊断为FR的患者(FR组).选择由于阻塞输尿管结石而没有FR而出现肾绞痛的连续患者作为对照组（非FR组）。患者按年龄组（<30、30-40、41-50和>50岁）分组，体重指数（BMI）等级，性别,合并症,肾积水等级,结石在输尿管中的位置，石头的大小(<3毫米，3-7毫米，且>7毫米)，和石头以前的地位。比较了基线患者和结石特征，并进行回归分析以确定FR的预测因子.
■共确定了50例FR患者，选择50例无FR患者的对照组。基线患者和结石人口统计学特征(P=0.42)，性别（P=0.275），BMI（P=0.672），合并症，肾积水分级(P=0.201),FR组和非FR组之间的结石位置（P=0.639）具有可比性。然而,两组间结石大小差异有统计学意义(P=0.014).在多变量分析中，研究发现,结石大小与FR发生率显著增加相关(比值比[OR]:6.5[1.235-34.434];P=0.027).此外，年龄在30~40岁之间的人群患FR的风险可能较低(OR:0.262[0.069~0.999];P=0.049).
■这项多中心研究表明，大小为3-7毫米的结石发生FR的机会增加了六倍，30至40岁的年龄组患FR的风险可能较低.
