关键词: acute respiratory infection disease burden epidemiology high risk risk factors

来  源:   DOI:10.3389/fmed.2024.1325236   PDF(Pubmed)

Abstract:
UNASSIGNED: Acute respiratory infections (ARIs) represent a significant public health concern in the U.S. This study aimed to describe the disease burden of ARIs and identify U.S. populations at high risk of developing complications.
UNASSIGNED: This scoping review searched PubMed and EBSCO databases to analyze U.S. studies from 2013 to 2022, focusing on disease burden, complications, and high-risk populations associated with ARIs.
UNASSIGNED: The study included 60 studies and showed that ARI is associated with a significant disease burden and healthcare resource utilization (HRU). In 2019, respiratory infection and tuberculosis caused 339,703 cases per 100,000 people, with most cases being upper respiratory infections and most deaths being lower respiratory infections. ARI is responsible for millions of outpatient visits, especially for influenza and pneumococcal pneumonia, and indirect costs of billions of dollars. ARI is caused by multiple pathogens and poses a significant burden on hospitalizations and outpatient visits. Risk factors for HRU associated with ARI include age, chronic conditions, and socioeconomic factors.
UNASSIGNED: The review underscores the substantial disease burden of ARIs and the influence of age, chronic conditions, and socioeconomic status on developing complications. It highlights the necessity for targeted strategies for high-risk populations and effective pathogen detection to prevent severe complications and reduce HRU.
摘要:
急性呼吸道感染(ARIs)是美国重大的公共卫生问题这项研究旨在描述ARIs的疾病负担,并确定患有并发症的高风险美国人群。
此范围审查搜索了PubMed和EBSCO数据库,以分析2013年至2022年的美国研究,重点是疾病负担,并发症,以及与ARIs相关的高危人群。
该研究包括60项研究,表明ARI与显着的疾病负担和医疗保健资源利用(HRU)有关。2019年,呼吸道感染和结核病每10万人中造成339703例,大多数病例是上呼吸道感染,大多数死亡是下呼吸道感染。ARI负责数百万的门诊就诊,尤其是流感和肺炎球菌肺炎,和数十亿美元的间接成本。ARI是由多种病原体引起的,并且对住院和门诊就诊造成显著负担。与ARI相关的HRU的危险因素包括年龄,慢性疾病,和社会经济因素。
该综述强调了ARIs的巨大疾病负担和年龄的影响,慢性疾病,和社会经济地位对发展并发症的影响。它强调了针对高危人群的针对性策略和有效的病原体检测以预防严重并发症并减少HRU的必要性。
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