PDF(Pubmed)
Abstract：
UNASSIGNED: To investigate the effects of acetylsalicylic acid (ASA) and the use of ultrasound elastography on testicular torsion.
UNASSIGNED: Herein, 6 equal groups of rats were formed (n: 48): control group, sham group, torsion/detorsion (T/D)-1 h group, T/D-1 h + ASA group, T/D-8 h group, and T/D-8 h + ASA group. Testicular torsion was created by rotating the left testis 720° clockwise. At 30 min before torsion, 100 mg/kg of ASA was injected intraperitoneally. Elastography was performed at 8 and 24 h. After orchiectomy, specimens were collected for histopathological evaluation.
UNASSIGNED: When comparing the left testicular volume (LV) parameters obtained from the elastography applied at 8 h, significant differences were observed between the following group pairs: the sham and T/D-8 h groups, T/D-1 h and T/D-8 h groups, and T/D-1 h + ASA and T/D-8 h groups (p = 0.004, p = 0.023, and p = 0.026, respectively). The mean LVS (velocity) (stiffness assessment) of the groups was similar at 8 h. When comparing the LV parameters at 24 h, significant differences were found between the T/D-1 h and T/D-8 h groups and between the T/D-8 h and T/D-8 h + ASA groups (p = 0.008 and p = 0.004, respectively). For the LVS mean values at 24 h, significant differences were found between the control and sham groups, sham and T/D-1 h groups, sham and T/D-8 h groups, and sham and T/D-8 h + ASA groups (p = 0.009, p = 0.021, p = 0.027, and p = 0.009, respectively).Histopathological evaluation showed a decrease in the morphological grades and an increase in the mean testicular injury scores in the T/D-1 h + ASA group compared to the T/D-1 h group. The T/D-8 h + ASA group had a higher morphological grade than the T/D-8 h group, whereas their mean testicular injury scores were similar.
UNASSIGNED: ASA treatment for testicular torsion was shown to be ineffective. Elastography can be a complementary method to Doppler ultrasonography in the diagnosis of testicular torsion and can guide surgeons in their approach to surgery.
UNASSIGNED: Herein, 6 equal groups of rats were formed (n: 48): control group, sham group, torsion/detorsion (T/D)-1 h group, T/D-1 h + ASA group, T/D-8 h group, and T/D-8 h + ASA group. Testicular torsion was created by rotating the left testis 720° clockwise. At 30 min before torsion, 100 mg/kg of ASA was injected intraperitoneally. Elastography was performed at 8 and 24 h. After orchiectomy, specimens were collected for histopathological evaluation.
UNASSIGNED: When comparing the left testicular volume (LV) parameters obtained from the elastography applied at 8 h, significant differences were observed between the following group pairs: the sham and T/D-8 h groups, T/D-1 h and T/D-8 h groups, and T/D-1 h + ASA and T/D-8 h groups (p = 0.004, p = 0.023, and p = 0.026, respectively). The mean LVS (velocity) (stiffness assessment) of the groups was similar at 8 h. When comparing the LV parameters at 24 h, significant differences were found between the T/D-1 h and T/D-8 h groups and between the T/D-8 h and T/D-8 h + ASA groups (p = 0.008 and p = 0.004, respectively). For the LVS mean values at 24 h, significant differences were found between the control and sham groups, sham and T/D-1 h groups, sham and T/D-8 h groups, and sham and T/D-8 h + ASA groups (p = 0.009, p = 0.021, p = 0.027, and p = 0.009, respectively).Histopathological evaluation showed a decrease in the morphological grades and an increase in the mean testicular injury scores in the T/D-1 h + ASA group compared to the T/D-1 h group. The T/D-8 h + ASA group had a higher morphological grade than the T/D-8 h group, whereas their mean testicular injury scores were similar.
UNASSIGNED: ASA treatment for testicular torsion was shown to be ineffective. Elastography can be a complementary method to Doppler ultrasonography in the diagnosis of testicular torsion and can guide surgeons in their approach to surgery.
摘要：
■研究乙酰水杨酸（ASA）和超声弹性成像对睾丸扭转的影响。
■这里，形成6个相等组的大鼠(n:48):对照组,假手术组,扭转/扭转（T/D）-1h组，T/D-1h+ASA组，T/D-8h组,T/D-8h+ASA组。通过顺时针旋转左睾丸720°来产生睾丸扭转。扭转前30分钟,腹膜内注射100mg/kg的ASA。弹性成像在8和24小时进行。睾丸切除术后，收集标本进行组织病理学评估。
■当比较从8小时施加的弹性成像获得的左睾丸体积（LV）参数时，在以下组对之间观察到显着差异：假手术和T/D-8h组，T/D-1h和T/D-8h组，和T/D-1h+ASA和T/D-8h组（分别为p=0.004，p=0.023和p=0.026）。各组的平均LVS（速度）（刚度评估）在8小时相似。当比较24小时的LV参数时，T/D-1h和T/D-8h组之间以及T/D-8h和T/D-8h+ASA组之间存在显著差异(分别为p=0.008和p=0.004).对于24小时的LVS平均值，对照组和假手术组之间存在显著差异，假手术组和T/D-1h组，假手术组和T/D-8h组，和假手术组和T/D-8h+ASA组（分别为p=0.009，p=0.021，p=0.027和p=0.009）。组织病理学评估显示，与T/D-1h组相比，T/D-1hASA组的形态学等级降低，平均睾丸损伤评分增加。T/D-8h+ASA组的形态学分级高于T/D-8h组,而他们的平均睾丸损伤评分相似。
■ASA治疗睾丸扭转无效。弹性成像可以作为诊断睾丸扭转的多普勒超声检查的补充方法，并可以指导外科医生的手术方法。
■这里，形成6个相等组的大鼠(n:48):对照组,假手术组,扭转/扭转（T/D）-1h组，T/D-1h+ASA组，T/D-8h组,T/D-8h+ASA组。通过顺时针旋转左睾丸720°来产生睾丸扭转。扭转前30分钟,腹膜内注射100mg/kg的ASA。弹性成像在8和24小时进行。睾丸切除术后，收集标本进行组织病理学评估。
■当比较从8小时施加的弹性成像获得的左睾丸体积（LV）参数时，在以下组对之间观察到显着差异：假手术和T/D-8h组，T/D-1h和T/D-8h组，和T/D-1h+ASA和T/D-8h组（分别为p=0.004，p=0.023和p=0.026）。各组的平均LVS（速度）（刚度评估）在8小时相似。当比较24小时的LV参数时，T/D-1h和T/D-8h组之间以及T/D-8h和T/D-8h+ASA组之间存在显著差异(分别为p=0.008和p=0.004).对于24小时的LVS平均值，对照组和假手术组之间存在显著差异，假手术组和T/D-1h组，假手术组和T/D-8h组，和假手术组和T/D-8h+ASA组（分别为p=0.009，p=0.021，p=0.027和p=0.009）。组织病理学评估显示，与T/D-1h组相比，T/D-1hASA组的形态学等级降低，平均睾丸损伤评分增加。T/D-8h+ASA组的形态学分级高于T/D-8h组,而他们的平均睾丸损伤评分相似。
■ASA治疗睾丸扭转无效。弹性成像可以作为诊断睾丸扭转的多普勒超声检查的补充方法，并可以指导外科医生的手术方法。
