PDF(Pubmed)
Abstract：
UNASSIGNED: The firing rate of the mirror neuron system in monkeys decreases systematically with more repetitions. The aim of this study is to investigate whether the activity of the mirror neuron system varies based on the observed movement and the contents of the action, as well as whether there is inhibition in the mirror neuron system when humans observe repeated actions. If inhibition is present, the second question of the study is whether it is related to the organization of the observed action.
UNASSIGNED: Fourteen healthy volunteers participated in the study. Transcranial magnetic stimulation was applied to the left primary motor cortex and motor evoked potentials (MEPs) were recorded from the right first dorsal interosseous and abductor pollicis brevis muscles while the participants were watching videos specially prepared for the study.
UNASSIGNED: There were no significant changes in MEP amplitudes compared to baseline MEPs while observing aimless action. However, while participants watched the repeated action video, the mean MEP amplitude increased at the beginning of the movement, but neither facilitation nor inhibition was detected when the participants watched the phase of grasping the object of the action compared to the baseline MEP amplitude. On the other hand, while participants were watching different activities, an increased MEP amplitude was observed at the beginning of the movement and in the grasping of the object of the action. Additionally, there was no significant reduction in MEP amplitude during any movement stages while observing the repeated action video.
UNASSIGNED: The findings of this study suggest that the activation of the mirror neuron system in humans depends on the content and stages of the observed movement. Additionally, there was no inhibition or systematic reduction in MEP amplitudes while watching a repeated action.
UNASSIGNED: Fourteen healthy volunteers participated in the study. Transcranial magnetic stimulation was applied to the left primary motor cortex and motor evoked potentials (MEPs) were recorded from the right first dorsal interosseous and abductor pollicis brevis muscles while the participants were watching videos specially prepared for the study.
UNASSIGNED: There were no significant changes in MEP amplitudes compared to baseline MEPs while observing aimless action. However, while participants watched the repeated action video, the mean MEP amplitude increased at the beginning of the movement, but neither facilitation nor inhibition was detected when the participants watched the phase of grasping the object of the action compared to the baseline MEP amplitude. On the other hand, while participants were watching different activities, an increased MEP amplitude was observed at the beginning of the movement and in the grasping of the object of the action. Additionally, there was no significant reduction in MEP amplitude during any movement stages while observing the repeated action video.
UNASSIGNED: The findings of this study suggest that the activation of the mirror neuron system in humans depends on the content and stages of the observed movement. Additionally, there was no inhibition or systematic reduction in MEP amplitudes while watching a repeated action.
摘要：
■猴子的镜像神经元系统的放电率随着更多的重复而系统地降低。这项研究的目的是调查镜像神经元系统的活动是否根据观察到的运动和动作的内容而变化，以及当人类观察到重复动作时，镜像神经元系统中是否存在抑制。如果存在抑制作用，研究的第二个问题是它是否与观察到的行动的组织有关。
■14名健康志愿者参与了这项研究。将经颅磁刺激应用于左侧初级运动皮层，并记录了右侧第一背侧骨间和外展肌的运动诱发电位（MEPs），而参与者正在观看专门为研究准备的视频。
■与基线MEP相比，MEP振幅没有显着变化，同时观察到无目的的动作。然而,当参与者观看重复的动作视频时，平均MEP振幅在运动开始时增加，但与基线MEP振幅相比,当参与者观察抓握动作对象的阶段时,未检测到促进或抑制.另一方面,当参与者观看不同的活动时，在运动开始和抓握动作对象时观察到MEP振幅增加。此外,在观察重复动作视频时,在任何运动阶段,MEP振幅均无显著降低.
■这项研究的结果表明，人类中镜像神经元系统的激活取决于观察到的运动的内容和阶段。此外,观察重复动作时,MEP振幅没有抑制或系统性降低.
■14名健康志愿者参与了这项研究。将经颅磁刺激应用于左侧初级运动皮层，并记录了右侧第一背侧骨间和外展肌的运动诱发电位（MEPs），而参与者正在观看专门为研究准备的视频。
■与基线MEP相比，MEP振幅没有显着变化，同时观察到无目的的动作。然而,当参与者观看重复的动作视频时，平均MEP振幅在运动开始时增加，但与基线MEP振幅相比,当参与者观察抓握动作对象的阶段时,未检测到促进或抑制.另一方面,当参与者观看不同的活动时，在运动开始和抓握动作对象时观察到MEP振幅增加。此外,在观察重复动作视频时,在任何运动阶段,MEP振幅均无显著降低.
■这项研究的结果表明，人类中镜像神经元系统的激活取决于观察到的运动的内容和阶段。此外,观察重复动作时,MEP振幅没有抑制或系统性降低.
