临床相关的 GABARAP 缺乏消除了硼替佐米诱导的多发性骨髓瘤中的免疫原性细胞死亡。
关键词: Immunotherapy autophagy danger associated molecular pattern phagocytosis
Mesh : Multiple Myeloma / drug therapy pathology immunology genetics metabolism Humans Bortezomib / pharmacology therapeutic use Adaptor Proteins, Signal Transducing / genetics metabolism deficiency Antineoplastic Agents / pharmacology therapeutic use Microtubule-Associated Proteins / genetics metabolism Apoptosis Regulatory Proteins / genetics metabolism Immunogenic Cell Death / drug effects Cell Line, Tumor Autophagy / drug effects Calreticulin / metabolism genetics
来 源:
DOI:10.1080/2162402X.2024.2360275
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