%0 Journal Article
%T Clinically relevant GABARAP deficiency abrogates bortezomib-induced immunogenic cell death in multiple myeloma.
%A Zhao L
%A Shen Z
%A Kroemer G
%A Kepp O
%J Oncoimmunology
%V 13
%N 1
%D 2024
%M 38812570
暂无%R 10.1080/2162402X.2024.2360275
%X Recently, it was revealed that the high-risk, poor-prognosis downregulation of GABA type A receptor-associated protein (GABARAP) causes a defect in both autophagy and surface exposure of calreticulin (CALR) in multiple myeloma (MM) cells responding to bortezomib. Hence, GABARAP-defective MM cells fail to undergo immunogenic cell death.